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Rasmus H Kirkegaard

Explore the profile of Rasmus H Kirkegaard including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 1213
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Recent Articles
1.
Vignolle A, Zehl M, Kirkegaard R, Vignolle G, Zotchev S
ACS Omega . 2025 Mar; 10(7):7163-7171. PMID: 40028056
Bacteria of the phylum Actinomycetota, particularly those of the genus , are prolific producers of secondary metabolites (SMs), many of which have been developed into antibiotics, immunosuppressants, and cancer therapeutics....
2.
Pereira F, Ge X, Kristensen J, Kirkegaard R, Maritsch K, Szamosvari D, et al.
Nat Microbiol . 2024 Nov; 9(12):3165-3183. PMID: 39572788
Many human-targeted drugs alter the gut microbiome, leading to implications for host health. However, the mechanisms underlying these effects are not well known. Here we combined quantitative microbiome profiling, long-read...
3.
Malfent F, Zehl M, Kirkegaard R, Oberhofer M, Zotchev S
Front Microbiol . 2024 Jul; 15:1408479. PMID: 38946903
Bacterial endophytes dwelling in medicinal plants represent an as yet underexplored source of bioactive natural products with the potential to be developed into drugs against various human diseases. For the...
4.
Pereira F, Ge X, Kristensen J, Kirkegaard R, Maritsch K, Zhu Y, et al.
bioRxiv . 2023 Nov; PMID: 38014294
Increasing evidence shows that many human-targeted drugs alter the gut microbiome, leading to implications for host health. However, much less is known about the mechanisms by which drugs target the...
5.
Mueller A, Daebeler A, Herbold C, Kirkegaard R, Daims H
ISME J . 2023 Sep; 17(11):2123-2133. PMID: 37749300
Nitrospirales, including the genus Nitrospira, are environmentally widespread chemolithoautotrophic nitrite-oxidizing bacteria. These mostly uncultured microorganisms gain energy through nitrite oxidation, fix CO, and thus play vital roles in nitrogen and...
6.
Singleton C, Petriglieri F, Kristensen J, Kirkegaard R, Michaelsen T, Andersen M, et al.
Nat Commun . 2021 Apr; 12(1):2009. PMID: 33790294
Microorganisms play crucial roles in water recycling, pollution removal and resource recovery in the wastewater industry. The structure of these microbial communities is increasingly understood based on 16S rRNA amplicon...
7.
Karst S, Ziels R, Kirkegaard R, Sorensen E, McDonald D, Zhu Q, et al.
Nat Methods . 2021 Jan; 18(2):165-169. PMID: 33432244
High-throughput amplicon sequencing of large genomic regions remains challenging for short-read technologies. Here, we report a high-throughput amplicon sequencing approach combining unique molecular identifiers (UMIs) with Oxford Nanopore Technologies (ONT)...
8.
Mueller A, Jung M, Strachan C, Herbold C, Kirkegaard R, Wagner M, et al.
ISME J . 2020 Oct; 15(3):732-745. PMID: 33067588
Chemolithoautotrophic nitrite-oxidizing bacteria (NOB) are key players in global nitrogen and carbon cycling. Members of the phylum Nitrospinae are the most abundant, known NOB in the oceans. To date, only...
9.
Brewer T, Albertsen M, Edwards A, Kirkegaard R, Rocha E, Fierer N
ISME J . 2019 Nov; 14(2):597-608. PMID: 31712737
Ribosomes are essential to cellular life and the genes for their RNA components are the most conserved and transcribed genes in bacteria and archaea. Ribosomal RNA genes are typically organized...
10.
McIlroy S, Onetto C, McIlroy B, Herbst F, Dueholm M, Kirkegaard R, et al.
Front Microbiol . 2018 Jun; 9:1004. PMID: 29875741
Enhanced biological phosphorus removal (EBPR) involves the cycling of biomass through carbon-rich (feast) and carbon-deficient (famine) conditions, promoting the activity of polyphosphate accumulating organisms (PAOs). However, several alternate metabolic strategies,...