Raphael Mattiuz
Overview
Explore the profile of Raphael Mattiuz including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
485
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Recent Articles
1.
Moon C, Belabed M, Park M, Mattiuz R, Puleston D, Merad M
Nat Rev Cancer
. 2025 Feb;
PMID: 39920276
Dendritic cells (DCs) are specialized antigen-presenting cells that are present at low abundance in the circulation and tissues; they serve as crucial immune sentinels by continually sampling their environment, migrating...
2.
Belabed M, Park M, Blouin C, Balan S, Moon C, Freed G, et al.
Nat Immunol
. 2025 Jan;
26(2):188-199.
PMID: 39838105
Maturation of conventional dendritic cells (cDCs) is crucial for maintaining tolerogenic safeguards against auto-immunity and for promoting immunogenic responses to pathogens and cancer. The subcellular mechanism for cDC maturation remains...
3.
Mattiuz R, Boumelha J, Hamon P, Le Berichel J, Vaidya A, Soong B, et al.
bioRxiv
. 2025 Jan;
PMID: 39763802
Tertiary lymphoid structures (TLS) are organized immune cell aggregates that arise in chronic inflammatory conditions. In cancer, TLS are associated with better prognosis and enhanced response to immunotherapy, making these...
4.
Park M, Le Berichel J, Hamon P, Wilk C, Belabed M, Yatim N, et al.
Science
. 2024 Sep;
386(6720):eadn0327.
PMID: 39236155
Age is a major risk factor for cancer, but how aging impacts tumor control remains unclear. In this study, we establish that aging of the immune system, regardless of the...
5.
Hegde S, Giotti B, Soong B, Halasz L, Le Berichel J, Magen A, et al.
bioRxiv
. 2024 Jul;
PMID: 38979166
Monocyte-derived macrophages (mo-macs) drive immunosuppression in the tumor microenvironment (TME) and tumor-enhanced myelopoiesis in the bone marrow (BM) fuels these populations. Here, we performed paired transcriptome and chromatin analysis over...
6.
LaMarche N, Hegde S, Park M, Maier B, Troncoso L, Le Berichel J, et al.
Nature
. 2023 Dec;
625(7993):166-174.
PMID: 38057662
Myeloid cells are known to suppress antitumour immunity. However, the molecular drivers of immunosuppressive myeloid cell states are not well defined. Here we used single-cell RNA sequencing of human and...
7.
Magen A, Hamon P, Fiaschi N, Soong B, Park M, Mattiuz R, et al.
Nat Med
. 2023 Jun;
29(6):1389-1399.
PMID: 37322116
Despite no apparent defects in T cell priming and recruitment to tumors, a large subset of T cell rich tumors fail to respond to immune checkpoint blockade (ICB). We leveraged...
8.
Mattiuz R, Brousse C, Ambrosini M, Cancel J, Bessou G, Mussard J, et al.
Clin Transl Immunology
. 2021 Jul;
10(7):e1305.
PMID: 34277006
Objectives: To better understand how immune responses may be harnessed against breast cancer, we investigated which immune cell types and signalling pathways are required for spontaneous control of a mouse...
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