Raphael J Crum
Overview
Explore the profile of Raphael J Crum including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
127
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0
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Recent Articles
1.
Capella-Monsonis H, Crum R, DAngelo W, Hussey G, Badylak S
Tissue Eng Part A
. 2025 Feb;
PMID: 39914815
Bioscaffolds composed of extracellular matrix (ECM) have been shown to promote a profound transition in macrophages and T-cells from a proinflammatory to a prohealing phenotype with associated site-appropriate and constructive...
2.
Capella-Monsonis H, Crum R, Hussey G, Badylak S
Adv Drug Deliv Rev
. 2024 Jun;
211:115347.
PMID: 38844005
Extracellular Matrix (ECM) scaffolds and biomaterials have been widely used for decades across a variety of diverse clinical applications and have been implanted in millions of patients worldwide. ECM-based biomaterials...
3.
Crum R, Huckestien B, Dwyer G, Mathews L, Nascari D, Hussey G, et al.
Sci Adv
. 2023 May;
9(20):eadf9016.
PMID: 37205761
Cytokine storm describes a life-threatening, systemic inflammatory syndrome characterized by elevated levels of proinflammatory cytokines and immune cell hyperactivation associated with multi-organ dysfunction. Matrix-bound nanovesicles (MBV) are a subclass of...
4.
Crum R, Capella-Monsonis H, Chang J, Dewey M, Kolich B, Hall K, et al.
Acta Biomater
. 2022 Nov;
155:113-122.
PMID: 36423817
Matrix-bound nanovesicles (MBV) are a distinct subtype of extracellular vesicles that are firmly embedded within biomaterials composed of extracellular matrix (ECM). MBV both store and transport a diverse, tissue specific...
5.
Behre A, Tashman J, Dikyol C, Shiwarski D, Crum R, Johnson S, et al.
Adv Healthc Mater
. 2022 Sep;
11(24):e2200866.
PMID: 36063047
Soft tissue injuries such as volumetric muscle loss (VML) are often too large to heal normally on their own, resulting in scar formation and functional deficits. Decellularized extracellular matrix (dECM)...
6.
Crum R, Johnson S, Jiang P, Jui J, Zamora R, Cortes D, et al.
Tissue Eng Part A
. 2022 Aug;
28(23-24):941-957.
PMID: 36039923
Skeletal muscle has a robust, inherent ability to regenerate in response to injury from acute to chronic. In severe trauma, however, complete regeneration is not possible, resulting in a permanent...
7.
Crum R, Hall K, Pineda Molina C, Hussey G, Graham E, Li H, et al.
NPJ Regen Med
. 2022 Feb;
7(1):13.
PMID: 35110573
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation and destruction of synovial joints affecting ~7.5 million people worldwide. Disease pathology is driven by an imbalance in the...
8.
Crum R, de Sa D, Su F, Lesniak B, Lin A
Shoulder Elbow
. 2021 Apr;
13(2):154-167.
PMID: 33897847
The purpose of this review was to update the complication profile of reverse total shoulder arthroplasty (rTSA) post-2010, given greater procedural familiarity, improved learning curves, enhanced implant designs, and increased...
9.
Crum R, Kay J, Lesniak B, Getgood A, Musahl V, de Sa D
Arthroscopy
. 2020 Oct;
37(3):1040-1052.
PMID: 33098947
Purpose: To examine existing literature on objective and patient-reported outcomes and complications after anterior cruciate ligament reconstruction (ACLR) with bone-quadriceps-tendon (B-QT) or soft tissue-quadriceps tendon (S-QT) to further clarify the...
10.
Hussey G, Nascari D, Saldin L, Kolich B, Lee Y, Crum R, et al.
Acta Biomater
. 2020 Apr;
108:77-86.
PMID: 32268241
Hydrogels composed of extracellular matrix (ECM) have been used as a substrate for 3D organoid culture, and in numerous preclinical and clinical applications to facilitate repair and reconstruction of a...