Raphael Breuer
Overview
Explore the profile of Raphael Breuer including associated specialties, affiliations and a list of published articles.
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Articles
32
Citations
454
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Recent Articles
1.
Wallach-Dayan S, Petukhov D, Ahdut-HaCohen R, Richter-Dayan M, Breuer R
Int J Mol Sci
. 2021 Mar;
22(4).
PMID: 33671651
By dint of the aging population and further deepened with the Covid-19 pandemic, lung disease has turned out to be a major cause of worldwide morbidity and mortality. The condition...
2.
Konikov-Rozenman J, Breuer R, Kaminski N, Wallach-Dayan S
Biomolecules
. 2020 Jul;
10(7).
PMID: 32630842
Regenerative capacity in vital organs is limited by fibrosis propensity. Idiopathic pulmonary fibrosis (IPF), a progressive lung disease linked with aging, is a classic example. In this study, we show...
3.
Bulvik R, Breuer R, Dvir-Ginzberg M, Reich E, Berkman N, Wallach-Dayan S
Biomolecules
. 2020 Jul;
10(7).
PMID: 32630813
In contrast to normal regenerating tissue, resistance to Fas- and FasL-positive T cell-induced apoptosis were detected in myofibroblasts from fibrotic-lungs of humans and mice following bleomycin (BLM) exposure. In this...
4.
Bulvik R, Biton M, Berkman N, Breuer R, Wallach-Dayan S
Int J Mol Sci
. 2020 Mar;
21(6).
PMID: 32210149
MicroRNAs (miRs) are known to limit gene expression at the post-transcriptional level and have important roles in the pathogenesis of various conditions, including acute lung injury (ALI) and fibrotic diseases...
5.
Nareznoi D, Konikov-Rozenman J, Petukhov D, Breuer R, Wallach-Dayan S
Cells
. 2020 Feb;
9(2).
PMID: 32053892
A prominent feature of obstructed tissue regeneration following injury in general, and fibrotic lung tissue in particular, is fibroblast proliferation and accumulation. The Fas/FasL apoptotic pathway has been shown to...
6.
Petukhov D, Richter-Dayan M, Fridlender Z, Breuer R, Wallach-Dayan S
Cells
. 2019 Oct;
8(10).
PMID: 31591327
CD44, an adhesion-molecule promoting cell-migration, is shown here to increase in stress conditions following bleomycin-induced apoptosis in alveolar epithelial cells (AECs), a main target of lung injury. In vivo, it...
7.
Cohen P, Breuer R, Wallach-Dayan S
Mediators Inflamm
. 2018 Jul;
2018:4638437.
PMID: 30002599
Lung fibrosis is characterized by abnormal accumulation of Thy-deficient fibroblasts in the interstitium of the alveolar space. We have previously shown in bleomycin-treated chimeric Thy1-deficient mice with wild-type lymphocytes that...
8.
Cohen P, Breuer R, Zisman P, Wallach-Dayan S
Mediators Inflamm
. 2015 Aug;
2015:942179.
PMID: 26300593
Lung fibrosis is characterized by abnormal accumulation of fibroblasts in the interstitium of the alveolar space. Two populations of myofibroblasts, distinguished by Thy1 expression, are detected in human and murine...
9.
Arish N, Cohen P, Golan-Gerstl R, Fridlender Z, Dayan M, Zisman P, et al.
PLoS One
. 2015 May;
10(5):e0126730.
PMID: 25951185
High doses of bleomycin administered to patients with lymphomas and other tumors lead to significant lung toxicity in general, and to apoptosis of epithelial cells, in particular. Apoptosis of alveolar...
10.
Wallach-Dayan S, Elkayam L, Golan-Gerstl R, Konikov J, Zisman P, Dayan M, et al.
J Autoimmun
. 2015 Mar;
59:67-76.
PMID: 25812467
Immune cells, particularly those expressing the ligand of the Fas-death receptor (FasL), e.g. cytotoxic T cells, induce apoptosis in 'undesirable' self- and non-self-cells, including lung fibroblasts, thus providing a means...