Rang Xu
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Explore the profile of Rang Xu including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
355
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Recent Articles
1.
Wang P, Shi W, Liu S, Shi Y, Jiang X, Li F, et al.
J Genet Genomics
. 2024 Jul;
51(9):934-946.
PMID: 39047937
Laterality is a crucial physiological process intricately linked to the cilium-centrosome complex during embryo development. Defects in the process can result in severe organ mispositioning. Coiled-coil domain containing 141 (CCDC141)...
2.
Wang P, Deng H, Xu R, Du J, Tao R
Zool Res
. 2024 May;
45(3):567-574.
PMID: 38757224
Most viruses and transposons serve as effective carriers for the introduction of foreign DNA up to 11 kb into vertebrate genomes. However, their activity markedly diminishes with payloads exceeding 11...
3.
Wei W, Li B, Li F, Sun K, Jiang X, Xu R
Genomics
. 2024 Apr;
116(3):110840.
PMID: 38580085
Conotruncal heart defects (CTD), subtypes of congenital heart disease, result from abnormal cardiac outflow tract development (OFT). FOXC1 and FOXC2 are closely related members of the forkhead transcription factor family...
4.
Ye J, Niu Y, Peng Y, Huang J, Wang H, Fu Q, et al.
Genomics
. 2023 Jul;
115(5):110676.
PMID: 37406974
Objective: Deleterious genetic variants comprise one cause of cardiac conotruncal defects (CTDs). Genes associated with CTDs are gradually being identified. In the present study, we aimed to explore the profile...
5.
Liu S, Wei W, Wang P, Liu C, Jiang X, Li T, et al.
PLoS Genet
. 2022 Dec;
18(12):e1010530.
PMID: 36459505
Defects in laterality pattern can result in abnormal positioning of the internal organs during the early stages of embryogenesis, as manifested in heterotaxy syndrome and situs inversus, while laterality defects...
6.
Zhao L, Huang S, Wei W, Zhang B, Shi W, Liang Y, et al.
Front Pediatr
. 2022 Oct;
10:996332.
PMID: 36245716
Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by motile ciliary dysfunction and impaired ultrastructure. Despite numerous studies, the genetic basis for about 30% of PCD cases remains...
7.
Qin X, Xu M, Ye J, Niu Y, Wu Y, Xu R, et al.
Hum Genomics
. 2022 Sep;
16(1):41.
PMID: 36123719
Background: Heterotaxy syndrome (HTX) is caused by aberrant left-right patterning early in embryonic development, which results in abnormal positioning and morphology of the thoracic and abdominal organs. Currently, genetic testing...
8.
Li B, Li T, Pu T, Liu C, Chen S, Sun K, et al.
Mol Genet Genomic Med
. 2021 Aug;
9(9):e1771.
PMID: 34363434
Background: Cardiac valvulogenesis is a highly conserved process among vertebrates and cause unidirectional flow of blood in the heart. It was precisely regulated by signal pathways such as VEGF, NOTCH,...
9.
Jiang X, Li T, Liu S, Fu Q, Li F, Chen S, et al.
Orphanet J Rare Dis
. 2021 Aug;
16(1):334.
PMID: 34332615
Background: TBX1 (T-box transcription factor 1) is a major candidate gene that likely contributes to the etiology of velo-cardio-facial syndrome/DiGeorge syndrome (VCFS/DGS). Although the haploinsufficiency of TBX1 in both mice...
10.
Jiang X, Li T, Li B, Wei W, Li F, Chen S, et al.
Clin Sci (Lond)
. 2021 Mar;
135(6):829-846.
PMID: 33720353
The endothelial-to-mesenchymal transition (EndMT) is a critical process that occurs during the development of the outflow tract (OFT). Malformations of the OFT can lead to the occurrence of conotruncal defect...