Randy R Brutkiewicz
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Explore the profile of Randy R Brutkiewicz including associated specialties, affiliations and a list of published articles.
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76
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1805
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Recent Articles
1.
Ping X, Xiong W, Priya R, Liu J, Wyatt-Johnson S, Brutkiewicz R, et al.
Epilepsia
. 2025 Feb;
PMID: 40019476
Objective: Posttraumatic epilepsy (PTE) that develops after a traumatic brain injury (TBI) cannot be prevented by current treatments. Although neuroinflammation is involved in epileptogenesis, a potential role for cellular immunity...
2.
Wyatt-Johnson S, Ackley S, Warren J, Priya R, Wan J, Liu S, et al.
Alzheimers Dement
. 2025 Jan;
21(2):e14480.
PMID: 39777865
Introduction: Plaques are a hallmark feature of Alzheimer's disease (AD). We found that the loss of mucosal-associated invariant T (MAIT) cells and their antigen-presenting molecule MR1 caused a delay in...
3.
Afify R, Lipsius K, Wyatt-Johnson S, Brutkiewicz R
Front Neurosci
. 2024 Dec;
18:1488382.
PMID: 39720231
In recent years, increasing evidence has highlighted the critical role of myeloid cells, specifically those that present antigen (APCs) in health and disease. These shape the progression and development of...
4.
Wyatt-Johnson S, Kersey H, Brutkiewicz R
J Neuroimmunol
. 2024 Mar;
390:578332.
PMID: 38537322
Emerging evidence has supported a role for the immune system and liver in Alzheimer's disease (AD). However, our understanding of how hepatic immune cells are altered in AD is limited....
5.
Wyatt-Johnson S, Afify R, Brutkiewicz R
J Allergy Clin Immunol
. 2024 Feb;
153(4):913-923.
PMID: 38365015
The immune system classically consists of 2 lines of defense, innate and adaptive, both of which interact with one another effectively to protect us against any pathogenic threats. Importantly, there...
6.
Shrinivasan R, Wyatt-Johnson S, Brutkiewicz R
Brain Behav Immun
. 2023 Dec;
116:321-328.
PMID: 38157945
Mucosal-associated invariant T (MAIT) cells are a subpopulation of innate-like T cells that can be found throughout the body, predominantly in mucosal sites, the lungs and in the peripheral blood....
7.
Wu X, Liu J, Li W, Khan M, Dai H, Tian J, et al.
bioRxiv
. 2023 Oct;
PMID: 37905092
Significance Statement: The cell surface molecule, CD1d, is known to be recognized by cells of the immune system. To our knowledge, this is the first observation that the CD1d molecule...
8.
Wyatt-Johnson S, Kersey H, Codocedo J, Newell K, Landreth G, Lamb B, et al.
J Neuroinflammation
. 2023 Mar;
20(1):78.
PMID: 36944969
Background: Neuroinflammation is an important feature of Alzheimer's disease (AD). Understanding which aspects of the immune system are important in AD may lead to new therapeutic approaches. We study the...
9.
Wang J, Toregrosa-Allen S, Elzey B, Utturkar S, Lanman N, Bernal-Crespo V, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(45).
PMID: 34740973
Tumor antigen heterogeneity, a severely immunosuppressive tumor microenvironment (TME) and lymphopenia resulting in inadequate immune intratumoral trafficking, have rendered glioblastoma (GBM) highly resistant to therapy. To address these obstacles, here...
10.
Li P, Walsh J, Lopez K, Isidan A, Zhang W, Chen A, et al.
Sci Rep
. 2021 Aug;
11(1):16967.
PMID: 34400757
No abstract available.