Randy Diaz-Tapia
Overview
Explore the profile of Randy Diaz-Tapia including associated specialties, affiliations and a list of published articles.
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7
Citations
102
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0
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Recent Articles
1.
Xiang Y, Xu J, McGovern B, Ranzenigo A, Huang W, Sang Z, et al.
Cell
. 2024 Oct;
187(24):6966-6980.e23.
PMID: 39447570
Pathogens constantly evolve and can develop mutations that evade host immunity and treatment. Addressing these escape mechanisms requires targeting evolutionarily conserved vulnerabilities, as mutations in these regions often impose fitness...
2.
Sakai A, Singh G, Khoshbakht M, Bittner S, Lohr C, Diaz-Tapia R, et al.
Mol Ther Nucleic Acids
. 2024 Oct;
35(4):102331.
PMID: 39376996
Further development of direct-acting antiviral agents against human SARS-CoV-2 infections remains a public health priority. Here, we report that an antisense peptide-conjugated morpholino oligomer (PPMO) named 5'END-2, targeting a highly...
3.
Lee A, Amick I, Aschenbrenner J, Barr H, Benjamin J, Brandis A, et al.
bioRxiv
. 2024 Sep;
PMID: 39229055
A strategy for pandemic preparedness is the development of antivirals against a wide set of viral targets with complementary mechanisms of action. SARS-CoV-2 nsp3-mac1 is a viral macrodomain with ADP-ribosylhydrolase...
4.
Rosales R, McGovern B, Rodriguez M, Leiva-Rebollo R, Diaz-Tapia R, Benjamin J, et al.
Antiviral Res
. 2024 Jul;
230:105970.
PMID: 39067667
Variants of SARS-CoV-2 pose significant challenges in public health due to their increased transmissibility and ability to evade natural immunity, vaccine protection, and monoclonal antibody therapeutics. The emergence of the...
5.
Prabhu M, Yang Y, Johnston C, Murphy E, Ketas T, Diaz-Tapia R, et al.
Am J Obstet Gynecol MFM
. 2022 Nov;
5(2):100796.
PMID: 36334723
Background: For some vaccine-preventable diseases, the immunologic response to vaccination is altered by a pregnant state. The effect of pregnancy on SARS-CoV-2 vaccine response remains unclear. Objective: We sought to...
6.
Ketas T, Chaturbhuj D, Cruz Portillo V, Francomano E, Golden E, Chandrasekhar S, et al.
Pathog Immun
. 2021 Jun;
6(1):116-134.
PMID: 34136730
The approved Pfizer and Moderna mRNA vaccines are well known to induce serum antibody responses to the SARS-CoV-2 Spike (S)-protein. However, their abilities to elicit mucosal immune responses have not...
7.
Ketas T, Chaturbhuj D, Cruz-Portillo V, Francomano E, Golden E, Chandrasekhar S, et al.
bioRxiv
. 2021 Mar;
PMID: 33758842
Vaccines are critical for curtailing the COVID-19 pandemic (1, 2). In the USA, two highly protective mRNA vaccines are available: BNT162b2 from Pfizer/BioNTech and mRNA-1273 from Moderna (3, 4). These...