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Randolph F Helfrich

Explore the profile of Randolph F Helfrich including associated specialties, affiliations and a list of published articles. Areas
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Articles 33
Citations 1728
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Recent Articles
1.
Cross Z, Helfrich R, Corcoran A, Dede A, Kohler M, Coussens S, et al.
J Neurosci . 2024 Nov; 45(3. PMID: 39572236
Sentence comprehension involves the decoding of both semantic and grammatical information, a process fundamental to communication. As with other complex cognitive processes, language comprehension relies, in part, on long-term memory....
2.
Hahn M, Lendner J, Anwander M, Slama K, Knight R, Lin J, et al.
Prog Neurobiol . 2024 Oct; 242:102672. PMID: 39369838
Sleep constitutes a brain state of disengagement from the external world that supports memory consolidation and restores cognitive resources. The precise mechanisms how sleep and its varied stages support information...
3.
Lendner J, Helfrich R
Trends Neurosci . 2024 Sep; 47(11):853-855. PMID: 39327160
Recent research by Parks, Schneider, and colleagues demonstrates that brain states during rodent sleep can be predicted from neural activity on millisecond and micrometer scales. These findings contradict the traditional...
4.
Banaie Boroujeni K, Helfrich R, Fiebelkorn I, Bentley N, Lin J, Knight R, et al.
bioRxiv . 2024 Sep; PMID: 39314423
Brain-wide communication supporting flexible behavior requires coordination between sensory and associative regions but how brain networks route sensory information at fast timescales to guide action remains unclear. Using spiking neural...
5.
Lendner J, Lin J, Larsson P, Helfrich R
J Neurosci . 2024 Aug; 44(42). PMID: 39187378
Human sleep exhibits multiple, recurrent temporal regularities, ranging from circadian rhythms to sleep stage cycles and neuronal oscillations during nonrapid eye movement sleep. Moreover, recent evidence revealed a functional role...
6.
Kopf M, Martini J, Stier C, Ethofer S, Braun C, Li Hegner Y, et al.
eNeuro . 2024 Aug; 11(9). PMID: 39137987
Generalized epilepsy (GE) encompasses a heterogeneous group of hyperexcitability disorders that clinically manifest as seizures. At the whole-brain level, distinct seizure patterns as well as interictal epileptic discharges (IEDs) reflect...
7.
Weber J, Solbakk A, Blenkmann A, Llorens A, Funderud I, Leske S, et al.
Nat Commun . 2024 Jan; 15(1):637. PMID: 38245516
Contextual cues and prior evidence guide human goal-directed behavior. The neurophysiological mechanisms that implement contextual priors to guide subsequent actions in the human brain remain unclear. Using intracranial electroencephalography (iEEG),...
8.
Raposo I, Szczepanski S, Haaland K, Endestad T, Solbakk A, Knight R, et al.
Curr Biol . 2023 Oct; 33(22):4893-4904.e3. PMID: 37852264
Contemporary models conceptualize spatial attention as a blinking spotlight that sequentially samples visual space. Hence, behavior fluctuates over time, even in states of presumed "sustained" attention. Recent evidence has suggested...
9.
Lendner J, Niethard N, Mander B, van Schalkwijk F, Schuh-Hofer S, Schmidt H, et al.
Sci Adv . 2023 Aug; 9(34):eadj1895. PMID: 37624898
The proposed mechanisms of sleep-dependent memory consolidation involve the overnight regulation of neural activity at both synaptic and whole-network levels. Now, there is a lack of in vivo data in...
10.
van Schalkwijk F, Weber J, Hahn M, Lendner J, Inostroza M, Lin J, et al.
Prog Neurobiol . 2023 Jun; 227:102485. PMID: 37353109
Systems-level memory consolidation during sleep depends on the temporally precise interplay between cardinal sleep oscillations. Specifically, hippocampal ripples constitute a key substrate of the hippocampal-neocortical dialog underlying memory formation. Recently,...