Randell G Young
Overview
Explore the profile of Randell G Young including associated specialties, affiliations and a list of published articles.
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7
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826
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Recent Articles
1.
Kean T, Duesler L, Young R, Dadabayev A, Olenyik A, Penn M, et al.
J Drug Target
. 2011 Nov;
20(1):23-32.
PMID: 22047107
Directing stem cells to the heart is critical in producing an effective cell therapy for myocardial infarction (MI). Mesenchymal stem cells (MSCs) offer an exquisite drug delivery platform with environment-sensing...
2.
Walczak P, Zhang J, Gilad A, Kedziorek D, Ruiz-Cabello J, Young R, et al.
Stroke
. 2008 Mar;
39(5):1569-74.
PMID: 18323495
Background And Purpose: In animal models of stroke, functional improvement has been obtained after stem cell transplantation. Successful therapy depends largely on achieving a robust and targeted cell engraftment, with...
3.
Schuleri K, Amado L, Boyle A, Centola M, Saliaris A, Gutman M, et al.
Am J Physiol Heart Circ Physiol
. 2008 Mar;
294(5):H2002-11.
PMID: 18310523
The underlying mechanism(s) of improved left ventricular function (LV) due to mesenchymal stem cell (MSC) administration after myocardial infarction (MI) remains highly controversial. Myocardial regeneration and neovascularization, which leads to...
4.
Poh K, Sperry E, Young R, Freyman T, Barringhaus K, Thompson C
Int J Cardiol
. 2006 Aug;
117(3):360-4.
PMID: 16889857
Background: Efficacy of cellular cardiomyoplasty seems to occur in a dose-related manner. However, the safety of multiple transendomyocardial transplantation procedures to administer high cell dosages has not been previously reported....
5.
Kraitchman D, Tatsumi M, Gilson W, Ishimori T, Kedziorek D, Walczak P, et al.
Circulation
. 2005 Sep;
112(10):1451-61.
PMID: 16129797
Background: Recent results from animal studies suggest that stem cells may be able to home to sites of myocardial injury to assist in tissue regeneration. However, the histological interpretation of...
6.
Chapel A, Bertho J, Bensidhoum M, Fouillard L, Young R, Frick J, et al.
J Gene Med
. 2003 Dec;
5(12):1028-38.
PMID: 14661178
Background: Recent studies have suggested that ex vivo expansion of autologous hematopoietic cells could be a therapy of choice for the treatment of bone marrow failure. We investigated the potential...
7.
Awad H, Boivin G, Dressler M, Smith F, Young R, Butler D
J Orthop Res
. 2003 Apr;
21(3):420-31.
PMID: 12706014
Collagen gels were seeded with rabbit bone marrow-derived mesenchymal stem cells (MSCs) and contracted onto sutures at initial cell densities of 1, 4, and 8 million cells/ml. These MSC-collagen composites...