Rana Zahreddine
Overview
Explore the profile of Rana Zahreddine including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
133
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0
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Recent Articles
1.
Kaplan A, El-Samadi L, Zahreddine R, Amin G, Booz G, Zouein F
Acta Physiol (Oxf)
. 2025 Feb;
241(3):e70010.
PMID: 39960030
G protein-coupled receptor kinase 2 (GRK2) with its multidomain structure performs various crucial cellular functions under both normal and pathological conditions. Overexpression of GRK2 is linked to cardiovascular diseases, and...
2.
Santin Y, Chiesa M, Alfonso A, Doghri Y, Kang R, Haidar F, et al.
Sci Adv
. 2024 Dec;
10(50):eadt1670.
PMID: 39671481
Biological age, which reflects the physiological state of an individual, offers a better predictive value than chronological age for age-related diseases and mortality. Nonetheless, determining accurate functional features of biological...
3.
Abidi E, Diab R, Zahreddine R, Amin G, Kaplan A, Booz G, et al.
Biol Sex Differ
. 2024 Dec;
15(1):100.
PMID: 39633480
Smoking, particularly chronic smoking (CS), is a threat to global health, contributing to increased mortality and morbidity associated with cardiovascular disease (CVD). CS induces oxidative stress and endothelial dysfunction, which...
4.
Mickiewicz L, Zahreddine R, Cormier K, Peries S, Del Bello A, Laffargue M, et al.
Front Transplant
. 2024 Jul;
3:1260125.
PMID: 38993774
Introduction: Transplant vasculopathy (TV) is a major complication after solid organ transplantation, distinguished by an arterial intimal thickening that obstructs the vascular lumen and leads to organ rejection. To date,...
5.
Nasr M, Fay A, Lupieri A, Malet N, Darmon A, Zahreddine R, et al.
Arterioscler Thromb Vasc Biol
. 2023 Dec;
44(3):620-634.
PMID: 38152888
Background: The ability to respond to mechanical forces is a basic requirement for maintaining endothelial cell (ECs) homeostasis, which is continuously subjected to low shear stress (LSS) and high shear...
6.
Davezac M, Meneur C, Buscato M, Zahreddine R, Arnal J, Dalenc F, et al.
Biochem Pharmacol
. 2023 Jul;
214:115677.
PMID: 37419371
Breast cancer is the most common cancer in women. Over the past few decades, advances in cancer detection and treatment have significantly improved survival rate of breast cancer patients. However,...
7.
Helissen O, Kermorgant M, Dejean S, Mercadie A, Le Gonidec S, Zahreddine R, et al.
Life (Basel)
. 2023 Mar;
13(3).
PMID: 36983999
Whether in real or simulated microgravity, Humans or animals, the kinetics of cardiovascular adaptation and its regulation by the autonomic nervous system (ANS) remain controversial. In this study, we used...
8.
Davezac M, Zahreddine R, Buscato M, Smirnova N, Febrissy C, Laurell H, et al.
JCI Insight
. 2023 Feb;
8(5).
PMID: 36729672
The main estrogen, 17β-estradiol (E2), exerts several beneficial vascular actions through estrogen receptor α (ERα) in endothelial cells. However, the impact of other natural estrogens such as estriol (E3) and...
9.
Davezac M, Buscato M, Zahreddine R, Lacolley P, Henrion D, Lenfant F, et al.
Front Aging
. 2022 Jul;
2:727380.
PMID: 35821994
Cardiovascular diseases remain an age-related pathology in both men and women. These pathologies are 3-fold more frequent in men than in women before menopause, although this difference progressively decreases after...
10.
Favre J, Vessieres E, Guihot A, Proux C, Grimaud L, Rivron J, et al.
Elife
. 2021 Nov;
10.
PMID: 34842136
Estrogen receptor alpha (ERα) activation by estrogens prevents atheroma through its nuclear action, whereas plasma membrane-located ERα accelerates endothelial healing. The genetic deficiency of ERα was associated with a reduction...