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Ramasubbu Sankararamakrishnan

Explore the profile of Ramasubbu Sankararamakrishnan including associated specialties, affiliations and a list of published articles. Areas
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Articles 45
Citations 444
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Recent Articles
1.
Singh P, Ramanathan V, Sankararamakrishnan R
Protein Sci . 2024 Nov; 33(12):e5218. PMID: 39548825
Functional groups in the side-chains of at least 10 amino acids are mainly involved in tertiary interactions. However, structural and functional significance of intra-residue interactions has not been fully recognized....
2.
Muthukumaran R, Sankararamakrishnan R
ACS Bio Med Chem Au . 2024 Jun; 4(3):137-153. PMID: 38911907
NS1 in flaviviruses is the only nonstructural protein that is secretory and interacts with different cellular components of the host cell membrane. NS1 is localized in the ER as a...
3.
Avasthi I, Muthukumaran R, Prajapati R, Sankararamakrishnan R, Verma S
Chem Asian J . 2024 Jan; 19(6):e202301119. PMID: 38286758
We report three complexes of Cd and Hg with two purine rare tautomers, N9-(pyridin-2-ylmethyl)-N-methoxyadenine, L1 and N7-(pyridin-2-ylmethyl)-N-methoxyadenine, L2, highlighting diverse crystallographic signatures exhibited by them. Influence of substituents, binding sites,...
4.
Gupta A, Sankararamakrishnan R
Proteins . 2024 Jan; 93(1):320-340. PMID: 38243636
The recently discovered SWEET (Sugar Will Eventually be Exported Transporter) proteins are involved in the selective transport of monosaccharides and disaccharides. The prokaryotic counterparts, semiSWEETs, form dimers with each monomer...
5.
Dande R, Sankararamakrishnan R
Database (Oxford) . 2023 Mar; 2023. PMID: 36913438
Aquaporins and aquaglyceroporins belong to the superfamily of major intrinsic proteins (MIPs), and they transport water and other neutral solutes such as glycerol. These channel proteins are involved in vital...
6.
Reddy C, Sankararamakrishnan R
Proteins . 2022 Dec; 91(5):679-693. PMID: 36541866
Many steps in programmed cell death are evolutionarily conserved across different species. The Caenorhabditis elegans proteins CED-9, CED-4 and EGL-1 involved in apoptosis are respectively homologous to anti-apoptotic Bcl-2 proteins,...
7.
Reddy C, Sankararamakrishnan R
ACS Omega . 2021 Oct; 6(41):26976-26989. PMID: 34693118
Viruses have evolved strategies to prevent apoptosis of infected cells at early stages of infection. The viral proteins (vBcl-2s) from specific viral genes adopt a helical fold that is structurally...
8.
Reddy C, Manzar N, Ateeq B, Sankararamakrishnan R
Biochemistry . 2020 Nov; 59(45):4379-4394. PMID: 33146015
Interactions between pro- and anti-apoptotic Bcl-2 proteins decide the fate of the cell. The BH3 domain of pro-apoptotic Bcl-2 proteins interacts with the exposed hydrophobic groove of their anti-apoptotic counterparts....
9.
Mukherjee M, Gupta A, Sankararamakrishnan R
Biophys J . 2020 Jan; 118(4):846-860. PMID: 31968229
Formate/nitrite transporters (FNTs) selectively transport monovalent anions and are found in prokaryotes and lower eukaryotes. They play a significant role in bacterial growth and act against the defense mechanism of...
10.
Jain A, Kumar Verma R, Sankararamakrishnan R
J Membr Biol . 2018 Nov; 252(1):17-29. PMID: 30470864
Major intrinsic protein (MIP) superfamily contains water-transporting AQP1 and glycerol-specific GlpF belonging to two major phylogenetic groups, namely aquaporins (AQPs) and aquaglyceroporins (AQGPs). MIP channels have six transmembrane helices (TM1...