Ram Krishna Thakur
Overview
Explore the profile of Ram Krishna Thakur including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
332
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Recent Articles
1.
Warfvinge R, Geironson Ulfsson L, Dhapola P, Safi F, Sommarin M, Soneji S, et al.
Elife
. 2024 Nov;
12.
PMID: 39503729
The advent of tyrosine kinase inhibitors (TKIs) as treatment of chronic myeloid leukemia (CML) is a paradigm in molecularly targeted cancer therapy. Nonetheless, TKI-insensitive leukemia stem cells (LSCs) persist in...
2.
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
Safi F, Dhapola P, Warsi S, Sommarin M, Erlandsson E, Ungerback J, et al.
Cell Rep
. 2023 Oct;
42(10):113357.
PMID: 37851570
No abstract available.
3.
Concurrent stem- and lineage-affiliated chromatin programs precede hematopoietic lineage restriction
Safi F, Dhapola P, Warsi S, Sommarin M, Erlandsson E, Ungerback J, et al.
Cell Rep
. 2022 May;
39(6):110798.
PMID: 35545037
The emerging notion of hematopoietic stem and progenitor cells (HSPCs) as a low-primed cloud without sharply demarcated gene expression programs raises the question on how cellular-fate options emerge and at...
4.
Thakur R, Yadav V, Kumar A, Singh A, Pal K, Hoeppner L, et al.
Nucleic Acids Res
. 2014 Sep;
42(18):11589-600.
PMID: 25249619
Tumor metastasis refers to spread of a tumor from site of its origin to distant organs and causes majority of cancer deaths. Although >30 metastasis suppressor genes (MSGs) that negatively...
5.
Yadav V, Thakur R, Eckloff B, Baral A, Singh A, Halder R, et al.
Nucleic Acids Res
. 2014 Aug;
42(15):9602-11.
PMID: 25081206
Previous studies have analyzed patterns of transcription, transcription factor (TF) binding or mapped nucleosome occupancy across the genome. These suggest that the three aspects are genetically connected but the cause...
6.
Thakur R, Yadav V, Kumar A, Basundra R, Kar A, Halder R, et al.
Mol Cytogenet
. 2014 Jun;
7:I9.
PMID: 24940385
No abstract available.
7.
Yadav V, Kumar A, Mann A, Aggarwal S, Kumar M, Roy S, et al.
Nucleic Acids Res
. 2013 Oct;
42(2):764-73.
PMID: 24157835
Building molecular correlates of drug resistance in cancer and exploiting them for therapeutic intervention remains a pressing clinical need. To identify factors that impact drug resistance herein we built a...
8.
Subramaniam S, Thakur R, Yadav V, Nanda R, Chowdhury S, Agrawal A
J Carcinog
. 2013 Apr;
12:3.
PMID: 23599685
Lung cancer is one of the deadliest cancers worldwide, with the highest incidence and mortality amongst all cancers. While the prognosis of lung cancer is generally grim, with 5-year survival...
9.
Kar A, Saha D, Purohit G, Singh A, Kumar P, Yadav V, et al.
Nucleic Acids Res
. 2011 Dec;
40(6):2554-65.
PMID: 22135295
Analysis of chromatin-immunoprecipitation followed by sequencing (ChIP-seq) usually disregards sequence reads that do not map within binding positions (peaks). Using an unbiased approach, we analysed all reads, both that mapped...
10.
Thakur R, Yadav V, Kumar P, Chowdhury S
Naunyn Schmiedebergs Arch Pharmacol
. 2011 May;
384(4-5):397-406.
PMID: 21556888
Non-metastatic 23 [NM23/nucleoside diphosphate kinases (NDPK)] genes are the first discovered metastasis suppressor genes. More than two decades of research has demonstrated their roles in a variety of biological processes...