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Ralph Telgmann

Explore the profile of Ralph Telgmann including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 282
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Recent Articles
1.
Ghadimi M, Pelzer U, Besselink M, Siveke J, Telgmann R, Braren R, et al.
BMC Cancer . 2025 Feb; 25(1):208. PMID: 39915735
Background: Based on current guidelines, surgical treatment of hepatic oligometastases in patients with pancreatic ductal adenocarcinoma (PDAC) is not primarily recommended. Systematic chemotherapy is the therapy of choice for these...
2.
Prugger C, Heidrich J, Wellmann J, Dittrich R, Brand S, Telgmann R, et al.
Dtsch Arztebl Int . 2012 May; 109(17):303-10. PMID: 22611443
Background: Target values for cardiovascular risk factors in patients with coronary heart disease (CHD) are stated in guidelines for the prevention of cardiovascular disease. We studied secular trends in risk...
3.
Baitsch D, Bock H, Engel T, Telgmann R, Muller-Tidow C, Varga G, et al.
Arterioscler Thromb Vasc Biol . 2011 Feb; 31(5):1160-8. PMID: 21350196
Objective: Apolipoprotein E (apoE) exerts potent antiinflammatory effects. Here, we investigated the effect of apoE on the functional phenotype of macrophages. Methods And Results: Human apoE receptors very-low-density lipoprotein receptor...
4.
Hagedorn C, Telgmann R, Dordelmann C, Schmitz B, Hasenkamp S, Cambien F, et al.
Arterioscler Thromb Vasc Biol . 2009 Aug; 29(10):1638-43. PMID: 19661483
Objective: Osteoprotegerin (OPG) has been reported to be involved in the development of atherosclerotic disease, and OPG gene variation has been associated with plasma OPG levels and different cardiovascular disease...
5.
Schmidt-Petersen K, Brand E, Telgmann R, Nicaud V, Hagedorn C, Labreuche J, et al.
Atherosclerosis . 2009 Mar; 206(1):209-15. PMID: 19281985
We aimed at associating common osteopontin (OPN) gene variants with cardiovascular disease phenotypes.We scanned the OPN gene in 190 chromosomes from myocardial infarction (MI) patients and identified five variants in...
6.
Hsu H, Duning K, Meyer H, Stolting M, Weide T, Kreusser S, et al.
Am J Physiol Renal Physiol . 2009 Jan; 296(4):F780-9. PMID: 19129260
The CXC chemokine receptor 3 (CXCR3) has been linked to autoimmune and inflammatory disease, allograft rejection, and ischemic nephropathy. CXCR3 is expressed on endothelial and smooth muscle cells. Although a...
7.
Telgmann R, Dordelmann C, Brand E, Nicaud V, Hagedorn C, Pavenstadt H, et al.
FASEB J . 2008 Dec; 23(5):1303-13. PMID: 19103645
Insulin-like growth factor 1 (IGF1) exerts important endocrine and paracrine functions in the cardiovascular system. We identified the common variant -1411C>T in the IGF1 upstream promoter P1, located within several...
8.
Vischer P, Telgmann R, Schmitz B, Hasenkamp S, Schmidt-Petersen K, Beining K, et al.
Pharmacogenet Genomics . 2008 Sep; 18(11):1017-9. PMID: 18820595
In genome-wide studies, the intercellular adhesion molecule-1 (ICAM-1) locus has been associated with cardiovascular and inflammatory bowel diseases. To determine the functional relevance of five missense ICAM-1 variants (G241R; I316V;...
9.
Hasenkamp S, Telgmann R, Staessen J, Hagedorn C, Dordelmann C, Bek M, et al.
Hypertension . 2008 Aug; 52(4):737-46. PMID: 18711008
The G protein-coupled receptor kinase 4 is involved in renal sodium handling and blood pressure regulation. Missense variants have already been tested functionally and are associated with hypertension, but no...
10.
Tregouet D, Groop P, McGinn S, Forsblom C, Hadjadj S, Marre M, et al.
Diabetes . 2008 Jul; 57(10):2843-50. PMID: 18633107
Objective: Genetic and environmental factors modulate the susceptibility to diabetic nephropathy, as initiating and/or progression factors. The objective of the European Rational Approach for the Genetics of Diabetic Complications (EURAGEDIC)...