Ralph Gottschalk
Overview
Explore the profile of Ralph Gottschalk including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
24
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0
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Recent Articles
1.
Vandebriel R, Pennings J, Baken K, Pronk T, Boorsma A, Gottschalk R, et al.
Toxicol Sci
. 2010 Jun;
117(1):81-9.
PMID: 20566472
Many chemicals can induce allergic contact dermatitis. Because evaluation of skin sensitizing potential by animal testing is prohibited for cosmetics, and screening of many chemicals is required within Registration, Evaluation,...
2.
Kienhuis A, van de Poll M, Dejong C, Gottschalk R, van Herwijnen M, Boorsma A, et al.
Toxicol In Vitro
. 2009 Jun;
23(6):1163-9.
PMID: 19527782
A compound for which marked species differences have been reported in laboratory animals and humans is coumarin. In rats, metabolites of coumarin are highly toxic, whereas in humans, the compound...
3.
Kienhuis A, van de Poll M, Wortelboer H, van Herwijnen M, Gottschalk R, Dejong C, et al.
Toxicol Sci
. 2008 Nov;
107(2):544-52.
PMID: 19008212
The frequent use of rodent hepatic in vitro systems in pharmacological and toxicological investigations challenges extrapolation of in vitro results to the situation in vivo and interspecies extrapolation from rodents...