Ralph C Schimmer
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Explore the profile of Ralph C Schimmer including associated specialties, affiliations and a list of published articles.
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22
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Recent Articles
11.
Epstein S, Delmas P, Emkey R, Wilson K, Hiltbrunner V, Schimmer R
Maturitas
. 2006 Mar;
54(1):1-10.
PMID: 16522358
Oral daily bisphosphonates carry a potential for gastrointestinal (GI) adverse events, which has been partly addressed by introducing once-weekly regimens. Nevertheless, the need to follow inconvenient dosing instructions every week...
12.
Ettinger M, Felsenberg D, Harris S, Wasnich R, Skag A, Hiltbrunner V, et al.
J Rheumatol
. 2005 Oct;
32(10):1968-74.
PMID: 16206354
Objective: The risk of osteoporosis increases exponentially with age. Elderly patients, who are often frail, have declining functional status and take multiple medications, and require osteoporosis therapies that are not...
13.
Beck-Schimmer B, Rosenberger D, Neff S, Jamnicki M, Suter D, Fuhrer T, et al.
Anesthesiology
. 2005 Sep;
103(3):556-66.
PMID: 16129981
Background: Acute lung injury caused by gastric aspiration is a frequent occurrence in unconscious patients. Acute respiratory distress syndrome in association with gastric aspiration carries a mortality of up to...
14.
Neff S, Roth Zgraggen B, Neff T, Jamnicki-Abegg M, Suter D, Schimmer R, et al.
Am J Physiol Lung Cell Mol Physiol
. 2005 Aug;
290(1):L86-96.
PMID: 16100285
Respiratory epithelial cells play a crucial role in the inflammatory response in endotoxin-induced lung injury, an experimental model for acute lung injury. To determine the role of epithelial cells in...
15.
Beck-Schimmer B, Schwendener R, Pasch T, Reyes L, Booy C, Schimmer R
Respir Res
. 2005 Jun;
6:61.
PMID: 15972102
Background: Alveolar macrophages play an important role during the development of acute inflammatory lung injury. In the present study, in vivo alveolar macrophage depletion was performed by intratracheal application of...
16.
Chesnut C, Ettinger M, Miller P, Baylink D, Emkey R, Harris S, et al.
Curr Med Res Opin
. 2005 Apr;
21(3):391-401.
PMID: 15811208
Objectives: BONE (oral iBandronate Osteoporosis vertebral fracture trial in North America and Europe) determined whether less frequent dosing of ibandronate (dose-free interval > 2 months) provided similar antifracture efficacy to...
17.
Pillai G, Gieschke R, Goggin T, Jacqmin P, Schimmer R, Steimer J
Br J Clin Pharmacol
. 2004 Nov;
58(6):618-31.
PMID: 15563360
Aims: Ibandronate, a highly potent nitrogen-containing bisphosphonate, is the subject of an ongoing clinical development programme that aims to maximize the potential of simplified, less frequent oral and intravenous (i.v.)...
18.
Chesnut 3rd C, Skag A, Christiansen C, Recker R, Stakkestad J, Hoiseth A, et al.
J Bone Miner Res
. 2004 Jul;
19(8):1241-9.
PMID: 15231010
Unlabelled: Oral daily (2.5 mg) and intermittent ibandronate (between-dose interval of >2 months), delivering a similar cumulative exposure, were evaluated in 2946 osteoporotic women with prevalent vertebral fracture. Significant reduction...
19.
Madjdpour L, Kneller S, Booy C, Pasch T, Schimmer R, Beck-Schimmer B
Anesthesiology
. 2003 Nov;
99(6):1323-32.
PMID: 14639144
Background: Aspiration of acidic gastric contents leads to acute lung injury and is still one of the most common clinical events associated with acute lung injury. This study was performed...
20.
Cooper C, Emkey R, McDonald R, Hawker G, Bianchi G, Wilson K, et al.
J Clin Endocrinol Metab
. 2003 Oct;
88(10):4609-15.
PMID: 14557430
Adherence to oral daily bisphosphonate regimens in postmenopausal osteoporosis is currently suboptimal. Less frequent dosing regimens are likely to improve patient adherence and thus, potentially, patient outcomes. A multicenter, randomized,...