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Rakesh Bhatnagar

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Articles 122
Citations 1292
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Recent Articles
11.
Gl B, Rajput R, Gupta M, Dahiya P, Thakur J, Bhatnagar R, et al.
Biochem J . 2020 Oct; 477(21):4167-4190. PMID: 33030198
Drug repurposing is an alternative avenue for identifying new drugs to treat tuberculosis (TB). Despite the broad-range of anti-tubercular drugs, the emergence of multi-drug-resistant and extensively drug-resistant strains of Mycobacterium...
12.
Gogoi H, Mani R, Malik A, Sehrawat P, Bhatnagar R
Vaccines (Basel) . 2020 Oct; 8(4). PMID: 33019545
Aluminium salts have been the adjuvant of choice in more than 100 licensed vaccines. Here, we have studied the synergistic effect of aluminium hydroxide nanoparticles (AH np) and non-ionic surfactant-based...
13.
Kaur R, Tiwari A, Manish M, Maurya I, Bhatnagar R, Singh S
J Ethnopharmacol . 2020 Aug; 264:113230. PMID: 32853741
Ethnopharmacological Relevance: Gastrointestinal anthrax, a disease caused by Bacillus anthracis, remains an important but relatively neglected endemic disease of animals and humans in remote areas of the Indian subcontinent and...
14.
Manish M, Verma S, Kandari D, Kulshreshtha P, Singh S, Bhatnagar R
Expert Opin Biol Ther . 2020 Jul; 20(12):1405-1425. PMID: 32729741
Introduction: Vaccines and therapeutic antibodies are the most crucial components of anthrax prophylaxis (pre- and post-exposure) and treatment. The improvement in the availability and safety profile of vaccines and the...
15.
Sanduja P, Gupta M, Somani V, Yadav V, Dua M, Hanski E, et al.
Nat Commun . 2020 Jul; 11(1):3545. PMID: 32669564
Group A Streptococcus (GAS) infection causes a range of diseases, but vaccine development is hampered by the high number of serotypes. Here, using reverse vaccinology the authors identify SPy_2191 as...
16.
Banerjee A, Somani V, Chakraborty P, Bhatnagar R, Varshney R, Echeverria-Vega A, et al.
Curr Genomics . 2020 Jul; 20(7):491-507. PMID: 32655288
Background: Thermophilic bacilli in both aerobic or facultative anaerobic forms have been isolated for over a hundred years from different mesophilic or thermophilic environments as they are potential source of...
17.
Sharma S, Bhatnagar R, Gaur D
Indian J Microbiol . 2020 Jul; 60(3):283-296. PMID: 32655196
Human pathogens need to overcome an elaborate network of host defense mechanisms in order to establish their infection, colonization, proliferation and eventual dissemination. The interaction of pathogens with different effector...
18.
Garhyan J, Mohan S, Rajendran V, Bhatnagar R
Pathogens . 2020 May; 9(5). PMID: 32414000
One-third of the world's population is estimated to be latently infected with (Mtb). Recently, we found that dormant Mtb hides in bone marrow mesenchymal stem cells (BM-MSCs) post-chemotherapy in mice...
19.
Sharma S, Bhatnagar R, Gaur D
Front Immunol . 2020 Apr; 11:462. PMID: 32296419
poly-γ-D-glutamic acid (PGA) capsule is an essential virulent factor that helps the bacterial pathogen to escape host immunity. Like other encapsulated bacterial species, the capsule may also inhibit complement-mediated clearance...
20.
Gupta S, Mohan S, Somani V, Aggarwal S, Bhatnagar R
Pathogens . 2020 Feb; 9(2). PMID: 32102449
Currently used vaccines, strain 19 and RB51, comprises of live attenuated strains and prevent infection in animals. However, these vaccines pose potential risks to recipient animals such as attenuation reversal...