Rajinder Bhardwaj
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Explore the profile of Rajinder Bhardwaj including associated specialties, affiliations and a list of published articles.
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22
Citations
18
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Recent Articles
1.
Akhter S, Gazal S, Badroo G, Bhat M, Shikha D, Farooq S, et al.
Vet Res Commun
. 2025 Feb;
49(2):102.
PMID: 39921828
Lumpy skin disease (LSD) is a highly contagious and fatal transboundary viral disease of cattle and water buffaloes caused by the Lumpy Skin Disease virus (LSDV) which belongs to the...
2.
Bhardwaj R, Malatesta J, Madonia J, Anderson M, Morris B, Matschke K, et al.
Clin Transl Sci
. 2024 Nov;
17(12):e70048.
PMID: 39602316
Zavegepant is a calcitonin gene-related peptide receptor antagonist for acute migraine treatment. This Phase I, open-label, fixed-sequence study evaluated the effects of itraconazole (a strong cytochrome P450 3A4 [CYP3A4] and...
3.
Bertz R, Collins J, Madonia J, Bhardwaj R, Kamen L, Matschke K, et al.
Headache
. 2024 Nov;
65(3):484-494.
PMID: 39508426
Objective: To compare the rate and extent of absorption of zavegepant 10 mg (therapeutic dose) or 20 mg (supratherapeutic dose) nasal spray during a migraine attack versus non-migraine period, assess...
4.
Bhardwaj R, Collins J, Madonia J, Matschke K, Bertz R, Liu J
Headache
. 2024 Nov;
65(1):14-23.
PMID: 39501702
Objective: The potential for drug-drug interaction of multiple-dose intranasal zavegepant on the single-dose oral contraceptive ethinyl estradiol and levonorgestrel (EE-LNG) was evaluated. Background: Zavegepant (as a nasal spray) is a...
5.
Comisar C, Francis J, Hughes J, Bhardwaj R, Bertz R, Liu J
CPT Pharmacometrics Syst Pharmacol
. 2024 Nov;
14(1):179-191.
PMID: 39492601
Zavegepant (ZAVZPRET™) is a high-affinity, selective, small-molecule calcitonin gene-related peptide receptor antagonist available for acute treatment of migraine in adults. A population pharmacokinetic analysis was performed to describe zavegepant plasma...
6.
Bhardwaj R, Donohue M, Madonia J, Matschke K, Anderson M, Morris B, et al.
Headache
. 2024 Oct;
65(2):315-325.
PMID: 39364589
Objective: To evaluate the pharmacodynamic (PD) and pharmacokinetic (PK) interactions between zavegepant and sumatriptan in healthy adults. Background: Zavegepant is a high-affinity, selective, small-molecule calcitonin gene-related peptide receptor antagonist administered...
7.
Bhardwaj R, Morris B, Matschke K, Bertz R, Croop R, Liu J
Headache
. 2024 Oct;
65(2):291-302.
PMID: 39364583
Objective: Reported here are the results of four rimegepant phase I studies, in healthy participants, aimed at determining the in vivo potential of rimegepant (75 mg) for cytochrome P450 (CYP)...
8.
Bhardwaj R, Donohue M, Madonia J, Anderson M, Matschke K, Bertz R, et al.
Clin Transl Sci
. 2024 Sep;
17(10):e70015.
PMID: 39348235
Zavegepant, a high-affinity, selective, small-molecule calcitonin gene-related peptide receptor antagonist, is approved as a nasal spray for acute treatment of migraine in adults. This phase I, open-label, single-center, single-period, nonrandomized...
9.
Bhardwaj R, Donohue M, Madonia J, Morris B, Marbury T, Matschke K, et al.
Clin Transl Sci
. 2024 Jul;
17(7):e13813.
PMID: 39014555
Zavegepant, a high-affinity, selective, small-molecule calcitonin gene-related peptide (CGRP) receptor antagonist, is approved in the United States for acute treatment of migraine in adults. The effects of moderate hepatic impairment...
10.
Hughes J, Bertz R, Bhardwaj R, Donohue M, Madonia J, Anderson M, et al.
CPT Pharmacometrics Syst Pharmacol
. 2024 May;
13(6):1044-1054.
PMID: 38812357
Zavegepant is a novel gepant administered as a nasal spray approved in the United States at a 10 mg dose for the acute treatment of migraine with or without aura...