Raj Murali
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Explore the profile of Raj Murali including associated specialties, affiliations and a list of published articles.
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58
Citations
1174
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Recent Articles
1.
Newton A, Kandemir G, Joyce T, Murali R, Hayton M, Talwalkar S, et al.
J Hand Surg Eur Vol
. 2023 Mar;
48(7):641-647.
PMID: 36927271
The aim of this study was to ascertain the long-term revision rates of the Universal 2 wrist prosthesis in a previously published cohort of patients with rheumatoid arthritis. The time...
2.
Amin A, Jeong S, Gillick J, Sursal T, Murali R, Gandhi C, et al.
Int J Oncol
. 2021 Sep;
59(4).
PMID: 34523696
Mechanistic target of rapamycin (mTOR), which functions via two multiprotein complexes termed mTORC1 and mTORC2, is positioned in the canonical phosphoinositide 3‑kinase‑related kinase (PI3K)/AKT (PI3K/AKT) pathways. These complexes exert their...
3.
Jhanwar-Uniyal M, Wainwright J, Mohan A, Tobias M, Murali R, Gandhi C, et al.
Adv Biol Regul
. 2019 Apr;
72:51-62.
PMID: 31010692
Activation of Mechanistic target of rapamycin (mTOR) signaling plays a crucial role in tumorigenesis of numerous malignancies including glioblastoma (GB). The Canonical PI3K/Akt/mTOR signaling cascade is commonly upregulated due to...
4.
Cooper J, Ronecker J, Tobias M, Mohan A, Hillard V, Murali R, et al.
Anticancer Res
. 2018 Mar;
38(4):1859-1877.
PMID: 29599302
Brain metastases are the leading cause of morbidity and mortality among cancer patients, and are reported to occur in about 40% of cancer patients with metastatic disease in the United...
5.
Jhanwar-Uniyal M, Amin A, Cooper J, Das K, Schmidt M, Murali R
Adv Biol Regul
. 2017 Feb;
64:39-48.
PMID: 28189457
Activation of PI3K/Akt/mTOR (mechanistic target of rapamycin) signaling cascade has been shown in tumorigenesis of numerous malignancies including glioblastoma (GB). This signaling cascade is frequently upregulated due to loss of...
6.
Ruzicka J, Machova-Urdzikova L, Gillick J, Amemori T, Romanyuk N, Karova K, et al.
Cell Transplant
. 2016 Dec;
26(4):585-603.
PMID: 27938489
Three different sources of human stem cells-bone marrow-derived mesenchymal stem cells (BM-MSCs), neural progenitors (NPs) derived from immortalized spinal fetal cell line (SPC-01), and induced pluripotent stem cells (iPSCs)-were compared...
7.
Gillick J, Cooper J, Babu S, Das K, Murali R
World Neurosurg
. 2016 Jun;
92:582.e5-582.e8.
PMID: 27318309
Background: Complex regional pain syndrome (CRPS), formerly referred to as reflex sympathetic dystrophy, is a pain syndrome characterized by severe pain, altered autonomic and motor function, and trophic changes. CRPS...
8.
Jeevan D, Cooper J, Braun A, Murali R, Jhanwar-Uniyal M
Anticancer Res
. 2016 Feb;
36(2):523-32.
PMID: 26851006
Background: Brain metastases are the leading cause of morbidity and mortality among patients with disseminated cancer. The development of metastatic disease involves an orderly sequence of steps enabling tumor cells...
9.
Machova Urdzikova L, Karova K, Ruzicka J, Kloudova A, Shannon C, Dubisova J, et al.
Int J Mol Sci
. 2016 Jan;
17(1).
PMID: 26729105
Well known for its anti-oxidative and anti-inflammation properties, curcumin is a polyphenol found in the rhizome of Curcuma longa. In this study, we evaluated the effects of curcumin on behavioral...
10.
Neil J, Shannon C, Mohan A, Laurent D, Murali R, Jhanwar-Uniyal M
Int J Oncol
. 2016 Jan;
48(3):1045-52.
PMID: 26719046
The PI3K-AKT-mTOR signaling axis is central to the transformed phenotype of glioblastoma (GBM) cells, due to frequent loss of tumor suppressor PTEN (phosphatase and tensin homolog deleted on chromosome 10)....