Rainer Sachs
Overview
Explore the profile of Rainer Sachs including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
7
Citations
149
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lermer E, Streicher B, Sachs R, Raue M, Frey D
Risk Anal
. 2015 Jun;
36(3):623-37.
PMID: 26111548
Recent findings on construal level theory (CLT) suggest that abstract thinking leads to a lower estimated probability of an event occurring compared to concrete thinking. We applied this idea to...
2.
Radivoyevitch T, Siranart N, Hlatky L, Sachs R
AAPS J
. 2015 Feb;
17(2):447-56.
PMID: 25663652
We consider dosing regimens designed to cure patients by eradicating colony forming units (CFU) such as bacteria. In the field of "population" pharmaco-kinetics/dynamics (PK/PD), inter-individual variability (IIV) of patients is...
3.
Fakir H, Hlatky L, Li H, Sachs R
Med Phys
. 2013 Dec;
40(12):121716.
PMID: 24320502
Purpose: Optimal treatment planning for fractionated external beam radiation therapy requires inputs from radiobiology based on recent thinking about the "five Rs" (repopulation, radiosensitivity, reoxygenation, redistribution, and repair). The need...
4.
Girdhani S, Sachs R, Hlatky L
Radiat Res
. 2013 Feb;
179(3):257-72.
PMID: 23373900
An understanding of proton radiobiology is critical for optimization of both proton radiotherapy and assessment of carcinogenesis risk from space radiation. Although the physical aspects of proton beam radiobiology is...
5.
Levy D, Reeder C, Loucas B, Hlatky L, Chen A, Cornforth M, et al.
J Comput Biol
. 2007 Apr;
14(2):144-55.
PMID: 17456013
Ionizing radiation can damage cells by breaking both strands of DNA in multiple locations, essentially cutting chromosomes into pieces. The cell has enzymatic mechanisms to repair such breaks; however, these...
6.
Duesberg P, Li R, Sachs R, Fabarius A, Upender M, Hehlmann R
Drug Resist Updat
. 2007 Mar;
10(1-2):51-8.
PMID: 17387035
Current genetic and epigenetic theories of cancer-specific drug resistance do not adequately explain: (i) the karyotypic changes that coincide with resistance, (ii) the high rates at which cancer cells acquire...
7.
Li R, Hehlman R, Sachs R, Duesberg P
Cancer Genet Cytogenet
. 2005 Nov;
163(1):44-56.
PMID: 16271955
Conventional mutation-selection theories have failed to explain (i) how cancer cells become spontaneously resistant against cytotoxic drugs at rates of up to 10(-3) per cell generation, orders higher than gene...