Rainer Kalscheuer
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Explore the profile of Rainer Kalscheuer including associated specialties, affiliations and a list of published articles.
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96
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2193
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Recent Articles
1.
Knak T, Takada S, Illarionov B, Krisilia V, Pessanha de Carvalho L, Lungerich B, et al.
ACS Med Chem Lett
. 2025 Jan;
16(1):136-143.
PMID: 39811140
Multidrug-resistant pathogens pose a major threat to human health, necessitating the identification of new drug targets and lead compounds that are not susceptible to cross-resistance. This study demonstrates that novel...
2.
Gao Y, Frank M, Teusch N, Woschko D, Janiak C, Mandi A, et al.
Front Microbiol
. 2024 Oct;
15:1458622.
PMID: 39397793
Three sulfur-containing alkaloids aplospojaveedins A-C (1-3) with a hitherto undescribed carbon skeleton comprising octahy-dronaphthalene, , -unsaturated lactam and glycine-cysteine moieties were isolated from . Their structures were elucidated by 1D...
3.
Elnaggar M, Mostafa N, Elissawy A, Phutthacharoen K, Eckhardt P, Sandargo B, et al.
Fitoterapia
. 2024 Oct;
179:106254.
PMID: 39396652
Chemical prospection for the mycelial extract of the fungus Acremonium sp. Strain MNA-F-1, derived from the inner tissue of anise roots (Pimpnella anisum L., family Apiaceae), led to the isolation...
4.
Podlesainski D, Adeniyi E, Groner Y, Schulz F, Krisilia V, Rehberg N, et al.
Cell Chem Biol
. 2024 Jul;
31(10):1755-1771.e73.
PMID: 38981479
Spread of antimicrobial resistances urges a need for new drugs against Mycobacterium tuberculosis (Mtb) with mechanisms differing from current antibiotics. Previously, callyaerins were identified as promising anti-tubercular agents, representing a...
5.
Koliye P, Nouga Bissoue A, Ngoh Misse Mouelle E, Kwanga Nguikwie S, Zambo Owona C, Simons V, et al.
Z Naturforsch C J Biosci
. 2024 Jun;
79(11-12):371-376.
PMID: 38934215
Chemical investigation of the fungal endophyte sp. isolated from leaves of , collected in Cameroon, resulted in the previously undescribed 10-membered macrolide, and two known natural products. The structures of...
6.
Silva R, Hernandez M, Kalscheuer R, Steinbuchel A, Alvarez H
Appl Microbiol Biotechnol
. 2024 Jun;
108(1):375.
PMID: 38878165
The selection of oleaginous bacteria, potentially applicable to biotechnological approaches, is usually carried out by different expensive and time-consuming techniques. In this study, we used Oil Red O (ORO) as...
7.
Adeniyi E, Kruppa M, De Benedetti S, Ludwig K, Krisilia V, Wassenberg T, et al.
ACS Infect Dis
. 2024 Jun;
10(6):1958-1969.
PMID: 38841740
About 100,000 deaths are attributed annually to infections with methicillin-resistant (MRSA) despite concerted efforts toward vaccine development and clinical trials involving several preclinically efficacious drug candidates. This necessitates the development...
8.
Khelwati H, van Geelen L, Kalscheuer R, Muller T
Molecules
. 2024 May;
29(9).
PMID: 38731617
In this study, a library of 3,7-di(hetero)aryl-substituted 10-(3-trimethylammoniumpropyl)10-phenothiazine salts is prepared. These title compounds and their precursors are reversible redox systems with tunable potentials. The Hammett correlation gives a very...
9.
Abdullaziz M, Takada S, Illarionov B, Pessanha de Carvalho L, Sakamoto Y, Hofmann S, et al.
ACS Infect Dis
. 2024 Apr;
10(5):1739-1752.
PMID: 38647213
Reverse analogs of the phosphonohydroxamic acid antibiotic fosmidomycin are potent inhibitors of the nonmevalonate isoprenoid biosynthesis enzyme 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXR, IspC) of . Some novel analogs with large phenylalkyl...
10.
Cifuente J, Colleoni C, Kalscheuer R, Guerin M
Chem Rev
. 2024 Apr;
124(8):4863-4934.
PMID: 38606812
Bacteria have acquired sophisticated mechanisms for assembling and disassembling polysaccharides of different chemistry. α-d-Glucose homopolysaccharides, so-called α-glucans, are the most widespread polymers in nature being key components of microorganisms. Glycogen...