Rainer Grobholz
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Explore the profile of Rainer Grobholz including associated specialties, affiliations and a list of published articles.
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102
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2185
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Recent Articles
1.
Papagiannakis A, Kwiatkowski M, Wyler S, Mortezavi A, Manka L, Wettstein M, et al.
Cancer Med
. 2025 Jan;
14(1):e70485.
PMID: 39757796
Objective: While statins have demonstrated a variety of antineoplastic effects in preclinical studies, several retrospective clinical studies and observational studies have not shown a consistent chemopreventive benefit against prostate cancer...
2.
Hutmacher F, Doerig S, Grobholz R, Kohler H, Meyer P, Baumann P
Front Pediatr
. 2024 Nov;
12:1433852.
PMID: 39539768
Neonatal diagnosis of inflammatory bowel disease (IBD) proves challenging due to its non-specific symptoms. A term-born neonate showing states of inflammation and aphthae was treated for sepsis and candidiasis before...
3.
Perl T, Jacquemai M, Pedrazzi N, Grobholz R, Glaab R, Conen A, et al.
Infection
. 2024 Oct;
PMID: 39373951
Gas gangrene is a rare presentation of a necrotizing fasciitis, caused by Clostridium perfringens, C. septicum and other clostridial species. With its rapid progression it is a potentially life-threatening infection,...
4.
Rippa M, Schulze R, Kenyon G, Himstedt M, Kwiatkowski M, Grobholz R, et al.
Diagnostics (Basel)
. 2024 Aug;
14(15).
PMID: 39125553
In this work, several machine learning (ML) algorithms, both classical ML and modern deep learning, were investigated for their ability to improve the performance of a pipeline for the segmentation...
5.
Faryna K, Tessier L, Retamero J, Bonthu S, Samanta P, Singhal N, et al.
Mod Pathol
. 2024 Jul;
37(11):100563.
PMID: 39025402
The biopsy Gleason score is an important prognostic marker for prostate cancer patients. It is, however, subject to substantial variability among pathologists. Artificial intelligence (AI)-based algorithms employing deep learning have...
6.
Janowczyk A, Zlobec I, Walker C, Berezowska S, Huschauer V, Tinguely M, et al.
Virchows Arch
. 2023 Dec;
485(1):13-30.
PMID: 38112792
Integration of digital pathology (DP) into clinical diagnostic workflows is increasingly receiving attention as new hardware and software become available. To facilitate the adoption of DP, the Swiss Digital Pathology...
7.
Berezowska S, Cathomas G, Grobholz R, Henkel M, Jochum W, Koelzer V, et al.
Pathologie (Heidelb)
. 2023 Nov;
44(Suppl 3):222-224.
PMID: 37987817
Digital pathology (DP) is increasingly entering routine clinical pathology diagnostics. As digitization of the routine caseload advances, implementation of digital image analysis algorithms and artificial intelligence tools becomes not only...
8.
Grobholz R, Janowczyk A, Frei A, Kreutzfeldt M, Koelzer V, Zlobec I
Pathologie (Heidelb)
. 2023 Nov;
44(Suppl 3):225-228.
PMID: 37987815
The Swiss Digital Pathology Consortium (SDiPath) was founded in 2018 as a working group of the Swiss Society for Pathology with the aim of networking, training, and promoting digital pathology...
9.
Frei A, Oberson R, Baumann E, Perren A, Grobholz R, Lugli A, et al.
Mod Pathol
. 2023 Sep;
36(12):100335.
PMID: 37742926
Tumor cell fraction (TCF) estimation is a common clinical task with well-established large interobserver variability. It thus provides an ideal test bed to evaluate potential impacts of employing a tumor...
10.
Menna F, Billia F, Papazoglou A, Tschopp M, Grobholz R
Pathogens
. 2023 Aug;
12(8).
PMID: 37623942
A 78-year-old Ukrainian woman who had immigrated to Switzerland presented with a rapid growing subcutaneous infraorbital mass. Surgical excision of the mass revealed a well-circumscribed, encapsulated tumor, adherent to the...