Rahul M Visalakshan
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Explore the profile of Rahul M Visalakshan including associated specialties, affiliations and a list of published articles.
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11
Citations
105
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Recent Articles
1.
Franca C, Lima Verde M, Silva-Sousa A, Mansoorifar A, Athirasala A, Subbiah R, et al.
Sci Adv
. 2025 Jan;
11(2):eadp3789.
PMID: 39792671
A hallmark of chronic and inflammatory diseases is the formation of a fibrotic and stiff extracellular matrix (ECM), typically associated with abnormal, leaky microvascular capillaries. Mechanisms explaining how the microvasculature...
2.
Bright R, Visalakshan R, Simon J, Rokstad A, Ghazaryan A, Morsbach S, et al.
ACS Biomater Sci Eng
. 2024 Aug;
10(10):6230-6240.
PMID: 39213601
The adsorption of serum proteins on biomaterial surfaces is a critical determinant for the outcome of medical procedures and therapies, which involve inserting materials and devices into the body. In...
3.
Visalakshan R, Lowrey M, Sousa M, Helms H, Samiea A, Schutt C, et al.
Front Immunol
. 2023 Apr;
14:1162905.
PMID: 37081897
Augmenting adaptive immunity is a critical goal for developing next-generation cancer therapies. T and B cells infiltrating the tumor dramatically influence cancer progression through complex interactions with the local microenvironment....
4.
Bright R, Hayles A, Wood J, Ninan N, Palms D, Visalakshan R, et al.
Nanomaterials (Basel)
. 2022 Apr;
12(7).
PMID: 35407257
Inspired by observations that the natural topography observed on cicada and dragonfly wings may be lethal to bacteria, researchers have sought to reproduce these nanostructures on biomaterials with the goal...
5.
Gonzalez-Garcia L, MacGregor M, Visalakshan R, Lazarian A, Cavallaro A, Morsbach S, et al.
Nanomaterials (Basel)
. 2022 Feb;
12(4).
PMID: 35215013
Nanoparticles are widely used for biomedical applications such as vaccine, drug delivery, diagnostics, and therapeutics. This study aims to reveal the influence of nanoparticle surface functionalization on protein corona formation...
6.
Zhuang L, Visalakshan R, Kaur P
Cells
. 2021 Nov;
10(11).
PMID: 34831274
The well documented decline in the regenerative ability of ageing human skin has been attributed to many factors including genomic instability, telomere shortening, poor nutrient sensing, cellular senescence, and stem...
7.
Dabare P, Bachhuka A, Visalakshan R, Shirazi H, Ostriko K, Smith L, et al.
ACS Biomater Sci Eng
. 2021 Sep;
7(10):4921-4932.
PMID: 34477378
Cellular migration plays a vital role in many physiological processes. To elucidate the role of surface nanotopography on the downstream signaling pathways underlying cell migration, model surfaces having well-defined hill-like...
8.
Bright R, Hayles A, Fernandes D, Visalakshan R, Ninan N, Palms D, et al.
ACS Appl Mater Interfaces
. 2021 Aug;
13(32):38007-38017.
PMID: 34374279
The demand for medical implants globally has increased significantly due to an aging population amongst other reasons. Despite the overall increase in the survivorship of Ti6Al4V implants, implant infection rates...
9.
Hopp I, MacGregor M, Doherty K, Visalakshan R, Vasilev K, Williams R, et al.
ACS Biomater Sci Eng
. 2021 Jan;
5(6):2834-2845.
PMID: 33405588
Kidney disease is now recognized as a global health problem and is associated with increased morbidity and mortality, along with high economic costs. To develop new treatments for ameliorating kidney...
10.
Visalakshan R, MacGregor M, Sasidharan S, Ghazaryan A, Mierczynska-Vasilev A, Morsbach S, et al.
ACS Appl Mater Interfaces
. 2019 Jul;
11(31):27615-27623.
PMID: 31310498
The nature of the protein corona forming on biomaterial surfaces can affect the performance of implanted devices. This study investigated the role of surface chemistry and wettability on human serum-derived...