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Rahul B Chavan

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Articles 18
Citations 227
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Recent Articles
11.
Salunke N, Thipparaboina R, Chavan R, Lodagekar A, Mittapalli S, Nangia A, et al.
J Pharm Biomed Anal . 2017 Nov; 149:185-192. PMID: 29121573
Rufinamide (R) is a triazole derivative approved for the management of partial seizures and seizures associated with Lennox-Gastaut Syndrome, in November 2007. Crystal structure, solid state characterization, drug-excipient compatibility and...
12.
Chavan R, Bhargavi N, Lodagekar A, Shastri N
Drug Discov Today . 2017 Sep; 22(12):1835-1843. PMID: 28893511
Physical characterization of solid form of drug is of paramount importance as its biopharmaceutical properties and/or its processing behavior may be altered. Early identification and monitoring of solid state transformation...
13.
Pardhi V, Chavan R, Thipparaboina R, Thatikonda S, Naidu V, Shastri N
Int J Pharm . 2017 Jun; 528(1-2):202-214. PMID: 28596138
Recent reports on the anticancer potential of niclosamide have opened new avenues for anticancer treatment. Niclosamide belongs to the BCS class II, which is indicative of poor solubility and dissolution...
14.
Chavan R, Thipparaboina R, Kumar D, Shastri N
Int J Pharm . 2016 Nov; 515(1-2):403-415. PMID: 27771485
Solubility is one of the major problems associated with most of the new chemical entities that can be reasonably addressed by drug amorphization. However, being a high-energy form, it usually...
15.
Thipparaboina R, Kumar D, Chavan R, Shastri N
Drug Discov Today . 2016 Feb; 21(3):481-90. PMID: 26869329
Co-crystals have garnered the interest of the pharmaceutical industry with the introduction of regulatory guidelines by the US Food and Drug Administration (FDA) as a result of expanded patent portfolios....
16.
Chavan R, Modi S, Bansal A
Int J Pharm . 2015 Sep; 495(1):374-384. PMID: 26364711
Self emulsifying drug delivery system (SEDDS) has been increasingly used for improving the oral bioavailability of poorly water soluble drugs. SEDDS can be solidified by adsorbing them on different solid...
17.
Thipparaboina R, Chavan R, Kumar D, Modugula S, Shastri N
Colloids Surf B Biointerfaces . 2015 Aug; 135:291-308. PMID: 26263217
Multi-drug therapy is described as a simultaneous or sequential administration of two or more drugs with similar or different mechanisms of action and is recognized as a more efficient solution...
18.
Sai Gouthami K, Kumar D, Thipparaboina R, Chavan R, Shastri N
Int J Pharm . 2015 Jun; 491(1-2):26-34. PMID: 26068197
Improvement in dissolution of the drugs having poor solubility is a challenge in pharmaceutical industry. Micronization is one technique, employed for dissolution enhancement of cilostazol, a BCS class II drug....