Raffeal Bennett
Overview
Explore the profile of Raffeal Bennett including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
52
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Recent Articles
1.
Bartholomew G, Kraus S, Karas L, Carpaneto F, Bennett R, Sigman M, et al.
J Am Chem Soc
. 2024 Jan;
146(5):2950-2958.
PMID: 38286797
The selective modification of nitrogen heteroaromatics enables the development of new chemical tools and accelerates drug discovery. While methods that focus on expanding or contracting the skeletal structures of heteroaromatics...
2.
Hendrick N, Fraser D, Bennett R, Corazzata K, Adpressa D, Makarov A, et al.
J Pharm Biomed Anal
. 2023 Mar;
229:115350.
PMID: 37001275
Peptides have gained an increasing importance in drug discovery as potential therapeutics. Discovery efforts toward finding new, efficacious peptide-based therapeutics have increased the throughput of peptide development, allowing the rapid...
3.
Losacco G, Bennett R, Haidar Ahmad I, Barrientos R, DaSilva J, Dong Y, et al.
Angew Chem Int Ed Engl
. 2022 Sep;
61(45):e202208854.
PMID: 36111975
Generality in analytical chemistry can be manifested in impactful platforms that can streamline modern organic synthesis and biopharmaceutical processes. We herein introduce a hybrid separation technique named Dual-Gradient Unified Chromatography...
4.
Bennett R, Cohen R, Wang H, Pereira T, Haverick M, Loughney J, et al.
Anal Chem
. 2021 Dec;
94(3):1678-1685.
PMID: 34928586
The employment of ethylenediaminetetraacetic acid (EDTA) across several fields in chemistry and biology has required the creation of a high number of quantitative assays. Nonetheless, the determination of trace EDTA,...
5.
Dispas A, Clarke A, Grand-Guillaume Perrenoud A, Losacco L, Veuthey J, Gros Q, et al.
J Pharm Biomed Anal
. 2021 Jun;
203:114206.
PMID: 34146950
Modern supercritical fluid chromatography (SFC) is now a well-established technique, especially in the field of pharmaceutical analysis. We recently demonstrated the transferability and the reproducibility of a SFC-UV method for...
6.
Haidar Ahmad I, Bennett R, Makey D, Shchurik V, Lhotka H, Mann B, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2021 Apr;
1173:122587.
PMID: 33845343
Recent advances in biomedical and pharmaceutical processes has enabled a notable increase of protein- and peptide-based drug therapies and vaccines that often contain a higher-order structure critical to their efficacy....
7.
Bennett R, Pirrone G, Nowak T, Mukherjee D, Shchurik V, Mapelli C, et al.
Anal Chim Acta
. 2020 Dec;
1142:10-18.
PMID: 33280687
At the forefront of synthetic endeavors in the pharmaceutical industry, including drug discovery and high-throughput screening, timelines are tight and large quantities of pure chemical targets are rarely available. In...
8.
Wang H, Lhotka H, Bennett R, Potapenko M, Pickens C, Mann B, et al.
J Chromatogr A
. 2020 May;
1622:460895.
PMID: 32408991
Baseline separation and analysis of multicomponent mixtures of closely related pharmaceuticals using single column selectivity can often be challenging, requiring the combination of orthogonal stationary and mobile phase methods to...
9.
Pickens C, Haidar Ahmad I, Makarov A, Bennett R, Mann B, Regalado E
Anal Bioanal Chem
. 2020 Mar;
412(11):2655-2663.
PMID: 32128644
The analysis of complex mixtures of closely related species is quickly becoming a bottleneck in the development of new drug substances, reflecting the ever-increasing complexity of both fundamental biology and...
10.
Liu J, Makarov A, Bennett R, Haidar Ahmad I, DaSilva J, Reibarkh M, et al.
Anal Chem
. 2019 Sep;
91(21):13907-13915.
PMID: 31549812
Chromatographic separation, analysis and characterization of complex highly polar analyte mixtures can often be very challenging using conventional separation approaches. Analysis and purification of hydrophilic compounds have been dominated by...