Raffaella Morini
Overview
Explore the profile of Raffaella Morini including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
907
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0
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Recent Articles
1.
Tagliatti E, Bizzotto M, Morini R, Filipello F, Rasile M, Matteoli M
Immunol Rev
. 2024 Nov;
327(1):100-110.
PMID: 39508795
Environmental insults during early development heavily affect brain trajectories. Among these, maternal infections, high-fat diet regimens, and sleep disturbances pose a significant risk for neurodevelopmental derangements in the offspring. Notably,...
2.
Borreca A, Mantovani C, Desiato G, Corradini I, Filipello F, Elia C, et al.
Brain Behav Immun
. 2024 Feb;
117:493-509.
PMID: 38307446
In the last years, the hypothesis that elevated levels of proinflammatory cytokines contribute to the pathogenesis of neurodevelopmental diseases has gained popularity. IL-1 is one of the main cytokines found...
3.
Tagliatti E, Desiato G, Mancinelli S, Bizzotto M, Gagliani M, Faggiani E, et al.
Immunity
. 2023 Dec;
57(1):86-105.e9.
PMID: 38159572
Triggering receptor expressed on myeloid cells 2 (Trem2) is a myeloid cell-specific gene expressed in brain microglia, with variants that are associated with neurodegenerative diseases, including Alzheimer's disease. Trem2 is...
4.
Mirabella F, Desiato G, Mancinelli S, Fossati G, Rasile M, Morini R, et al.
Immunity
. 2021 Nov;
54(11):2611-2631.e8.
PMID: 34758338
Early prenatal inflammatory conditions are thought to be a risk factor for different neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy causes abnormal behavior in offspring, but whether these defects...
5.
Morini R, Bizzotto M, Perrucci F, Filipello F, Matteoli M
Front Immunol
. 2021 Mar;
12:640937.
PMID: 33708226
The role of microglia in controlling synapse homeostasis is becoming increasingly recognized by the scientific community. In particular, the microglia-mediated elimination of supernumerary synapses during development lays the basis for...
6.
Ghirardini E, Restelli E, Morini R, Bertani I, Ortolan D, Perrucci F, et al.
PLoS Pathog
. 2020 Dec;
16(12):e1009174.
PMID: 33351850
[This corrects the article DOI: 10.1371/journal.ppat.1008654.].
7.
Ghirardini E, Restelli E, Morini R, Bertani I, Ortolan D, Perrucci F, et al.
PLoS Pathog
. 2020 Jul;
16(7):e1008654.
PMID: 32673372
Prion protein (PrP) mutations are linked to genetic prion diseases, a class of phenotypically heterogeneous neurodegenerative disorders with invariably fatal outcome. How mutant PrP triggers neurodegeneration is not known. Synaptic...
8.
Scott-Hewitt N, Perrucci F, Morini R, Erreni M, Mahoney M, Witkowska A, et al.
EMBO J
. 2020 Jul;
39(16):e105380.
PMID: 32657463
Neuronal circuit assembly requires the fine balance between synapse formation and elimination. Microglia, through the elimination of supernumerary synapses, have an established role in this process. While the microglial receptor...
9.
Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, et al.
EMBO J
. 2018 Nov;
38(1).
PMID: 30396995
Control of synapse number and function in the developing central nervous system is critical to the formation of neural circuits. Astrocytes play a key role in this process by releasing...
10.
Morini R, Ferrara S, Perrucci F, Zambetti S, Pelucchi S, Marcello E, et al.
Front Mol Neurosci
. 2018 Sep;
11:313.
PMID: 30233314
Actin-based remodeling underlines spine morphogenesis and plasticity and is crucially involved in the processes that constantly reshape the circuitry of the adult brain in response to external stimuli, leading to...