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Raffaella Melzi

Explore the profile of Raffaella Melzi including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 1037
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Recent Articles
1.
Catarinella D, Melzi R, Mercalli A, Magistretti P, Tentori S, Gremizzi C, et al.
Lancet Diabetes Endocrinol . 2025 Feb; PMID: 39929222
Background: Islet transplantation has the potential to cure type 1 diabetes by restoring endogenous insulin production. However, its success relies on balancing improved glycaemic control with the risks of immunosuppressive...
2.
Sordi V, Monti P, Lampasona V, Melzi R, Pellegrini S, Keymeulen B, et al.
Front Endocrinol (Lausanne) . 2023 Jul; 14:1175640. PMID: 37409229
Aim: In a recent randomized, multicenter trial (NCT02814838) a short-term anti-inflammatory treatment with ladarixin (LDX; an inhibitor of the CXCR1/2 chemokine receptors) did not show benefit on preserving residual beta...
3.
Milardi G, Lorenzo B, Gerosa J, Barzaghi F, Di Matteo G, Omrani M, et al.
Eur J Immunol . 2022 May; 52(7):1171-1189. PMID: 35562849
Common variable immunodeficiency (CVID) is the most frequent primary antibody deficiency whereby follicular helper T (Tfh) cells fail to establish productive responses with B cells in germinal centers. Here, we...
4.
Laurenzi A, Caretto A, Molinari C, Mercalli A, Melzi R, Nano R, et al.
J Clin Endocrinol Metab . 2021 Oct; 107(3):e1009-e1019. PMID: 34718627
Purpose: To assess whether dysglycemia diagnosed during severe acute respiratory syndrome coronavirus 2 pneumonia may become a potential public health problem after resolution of the infection. In an adult cohort...
5.
Laurenzi A, Caretto A, Molinari C, Bazzigaluppi E, Brigatti C, Marzinotto I, et al.
Biology (Basel) . 2021 Aug; 10(8). PMID: 34439986
Aim: The aim of the current study was to compare clinical characteristics, laboratory findings, and major outcomes of patients hospitalized for COVID-19 pneumonia with COVID-associated hyperglycaemia or pre-existing diabetes. Methods:...
6.
Lampasona V, Secchi M, Scavini M, Bazzigaluppi E, Brigatti C, Marzinotto I, et al.
Diabetologia . 2020 Oct; 63(12):2548-2558. PMID: 33029657
Aims/hypothesis: The aim of the study was to characterise the humoral response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with diabetes. Demonstrating the ability to mount an...
7.
Nano R, Kerr-Conte J, Bosco D, Karlsson M, Lavallard V, Melzi R, et al.
Diabetes . 2019 Jul; 68(8):1541-1543. PMID: 31331988
In December 2018, and began requiring authors of papers reporting data obtained from studies on human islets to report critical characteristics of the human islets used for research. The islet...
8.
Balzano G, Maffi P, Nano R, Mercalli A, Melzi R, Aleotti F, et al.
Am J Transplant . 2018 Dec; 19(3):920-928. PMID: 30549450
Islet autotransplant is particularly attractive to prevent diabetes after extended pancreatectomy for benign or borderline/malignant pancreas disease. Between 2008 and 2018, 25 patients underwent left extended pancreatectomy (>60%) and islet...
9.
Maffi P, Nano R, Monti P, Melzi R, Sordi V, Mercalli A, et al.
Transplantation . 2018 Aug; 103(4):839-851. PMID: 30130323
Background: Results in murine and nonhuman primate suggested that the bone marrow (BM) might be an alternative site for pancreatic islet transplantation. Methods: We report the results of 2 clinical...
10.
Marzinotto I, Pellegrini S, Brigatti C, Nano R, Melzi R, Mercalli A, et al.
Sci Rep . 2017 Oct; 7(1):14051. PMID: 29070792
miR-204 has been proposed to modulate insulin expression in human pancreatic islets by regulating the expression of the MAFA transcript, and in turn insulin transcription. We investigated miR-204 expression in...