Rafal Pawlinski
Overview
Explore the profile of Rafal Pawlinski including associated specialties, affiliations and a list of published articles.
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80
Citations
3514
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Recent Articles
1.
Trebak F, Sako M, Grover S, Seanoon K, Pawlinski I, Moonla C, et al.
Blood Adv
. 2025 Mar;
PMID: 40086080
Sickle cell trait (SCT) is present in subjects who possess a single copy of the bS-globin gene mutation. While most affected individuals are asymptomatic, SCT is a well-established risk factor...
2.
Ellsworth P, Pawlinski I, Sielaty R, Ilich A, Prokopenko Y, Moonla C, et al.
Br J Haematol
. 2024 Jul;
205(4):1565-1569.
PMID: 39054759
Deformability and sickling of red blood cells (RBCs) from individuals with sickle cell trait (SCT) was evaluated under harsh biophysical conditions that mimic certain vascular beds in vivo. RBC deformability...
3.
Ballard-Kordeliski A, Lee R, OShaughnessy E, Kim P, Jones S, Pawlinski R, et al.
Blood
. 2024 May;
144(10):1116-1126.
PMID: 38820498
Interplay between platelets, coagulation factors, endothelial cells (ECs), and fibrinolytic factors is necessary for effective hemostatic plug formation. This study describes a 4-dimensional (4D) imaging platform to visualize and quantify...
4.
Ramadas N, Lowder K, Dutton J, Trebak F, Faes C, Griffin J, et al.
Blood Adv
. 2024 Apr;
8(12):3272-3283.
PMID: 38640339
Sickle cell disease (SCD) is a hereditary hemoglobinopathy marked by hemolytic anemia and vaso-occlusive events (VOEs). Chronic endothelial activation, inflammation, and coagulation activation contribute to vascular congestion, VOEs, and end-organ...
5.
Wan J, Dhrolia S, Kasthuri R, Prokopenko Y, Ilich A, Saha P, et al.
Blood Adv
. 2024 Apr;
8(12):3045-3057.
PMID: 38593231
Plasma kallikrein (PKa) is an important activator of factor XII (FXII) of the contact pathway of coagulation. Several studies have shown that PKa also possesses procoagulant activity independent of FXII,...
6.
Sparkenbaugh E, Henderson M, Miller-Awe M, Abrams C, Ilich A, Trebak F, et al.
Blood
. 2023 Jan;
141(15):1871-1883.
PMID: 36706361
A hypercoagulable state, chronic inflammation, and increased risk of venous thrombosis and stroke are prominent features in patients with sickle cell disease (SCD). Coagulation factor XII (FXII) triggers activation of...
7.
Liao Y, Xu Y, Arnold K, Zhang F, Li J, Sellers R, et al.
Proc Natl Acad Sci U S A
. 2023 Jan;
120(4):e2209528120.
PMID: 36649428
Sepsis is a lethal syndrome manifested by an unregulated, overwhelming inflammation from the host in response to infection. Here, we exploit the use of a synthetic heparan sulfate octadecasaccharide (18-mer)...
8.
Wan J, Tanratana P, Roest M, Gruber A, Pawlinski R, Wolberg A, et al.
Blood Adv
. 2022 Dec;
7(9):1915-1925.
PMID: 36583671
Thrombin generation (TG) assays serve as a valuable tool to study the amplifying roles of intrinsic pathway factors in human coagulation and provide functional insights into the increased bleeding observed...
9.
Reeves B, Kim S, Song J, Wilson K, Henderson M, Key N, et al.
Am J Hematol
. 2021 Nov;
97(2):E37-E40.
PMID: 34748652
No abstract available.
10.
Ilich A, Sparkenbaugh E, Wolberg A, Key N, Pawlinski R
J Thromb Haemost
. 2021 Oct;
19(11):2893-2894.
PMID: 34668297
No abstract available.