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Rafael Lancelotta

Explore the profile of Rafael Lancelotta including associated specialties, affiliations and a list of published articles. Areas
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Reckweg J, Uthaug M, Szabo A, Davis A, Lancelotta R, Mason N, et al.
J Neurochem . 2022 Feb; 162(1):128-146. PMID: 35149998
5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a naturally occurring tryptamine that primarily acts as an agonist at the 5-HT1A and 5-HT2A receptors, whereby affinity for the 5-HT1A subtype is highest. Subjective effects following...
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Uthaug M, Davis A, Haas T, Davis D, Dolan S, Lancelotta R, et al.
J Psychopharmacol . 2021 May; 36(3):309-320. PMID: 33949246
Background: Mescaline is a naturally occurring psychoactive phenethylamine found in several cacti and historically used ceremonially by Indigenous and Latin American populations. Broader recognition of its possible therapeutic value in...
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Agin-Liebes G, Haas T, Lancelotta R, Uthaug M, Ramaekers J, Davis A
ACS Pharmacol Transl Sci . 2021 Apr; 4(2):543-552. PMID: 33860184
Mescaline is a naturally occurring psychoactive alkaloid that has been used as a sacrament by Indigenous populations in spiritual ritual and healing ceremonies for millennia. Despite promising early preliminary research...
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Sherwood A, Claveau R, Lancelotta R, Kaylo K, Lenoch K
ACS Omega . 2020 Dec; 5(49):32067-32075. PMID: 33344861
To support clinical use, a multigram-scale process has been developed to provide 5-MeO-DMT, a psychedelic natural product found in the parotid gland secretions of the toad, . Several synthetic routes...
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Luoma J, Chwyl C, Bathje G, Davis A, Lancelotta R
J Psychoactive Drugs . 2020 Jun; 52(4):289-299. PMID: 32529966
After a two-decade hiatus in which research on psychedelics was essentially halted, placebo-controlled clinical trials of psychedelic-assisted therapy for mental health conditions have begun to be published. We identified nine...
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Uthaug M, Lancelotta R, Szabo A, Davis A, Riba J, Ramaekers J
Psychopharmacology (Berl) . 2019 Dec; 237(3):773-785. PMID: 31822925
Rationale: 5-methoxy-N,N-dimethyltryptamine is a psychotropic substance found in various plant and animal species and is synthetically produced. 5-methoxy-N,N-dimethyltryptamine is used in naturalistic settings for spiritual exploration, recreation, or to address...
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Davis A, So S, Lancelotta R, Barsuglia J, Griffiths R
Am J Drug Alcohol Abuse . 2019 Mar; 45(2):161-169. PMID: 30822141
Background: A recent epidemiological study suggested that 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) used for spiritual and recreational reasons is associated with subjective improvement in depression and anxiety. Further exploration of the potential psychotherapeutic...
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Barsuglia J, Davis A, Palmer R, Lancelotta R, Windham-Herman A, Peterson K, et al.
Front Psychol . 2018 Dec; 9:2459. PMID: 30574112
5-MeO-DMT is a psychoactive substance found in high concentrations in the bufotoxin of the Colorado River Toad (). Emerging evidence suggests that vaporized 5-MeO-DMT may occasion mystical experiences of comparable...
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Davis A, Barsuglia J, Lancelotta R, Grant R, Renn E
J Psychopharmacol . 2018 May; 32(7):779-792. PMID: 29708042
Background/aim: 5-Methoxy- N,N-dimethyltryptamine (5-MeO-DMT) is a psychoactive compound found in several plants and in high concentrations in Bufo alvarius toad venom. Synthetic, toad, and plant-sourced 5-MeO-DMT are used for spiritual...