Rafael Fissore
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Explore the profile of Rafael Fissore including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
493
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Recent Articles
1.
Arroyo-Salvo C, Rio S, Bogetti M, Plaza J, Miragaya M, Yaneff A, et al.
Andrology
. 2024 May;
13(2):382-395.
PMID: 38804843
Background: Factors contributing to the limited success of in vitro fertilization in horses remain to be studied. In this work, we elucidated the effect of different essential capacitation media components,...
2.
Nabi D, Bosi D, Gupta N, Thaker N, Fissore R, Brayboy L
Reproduction
. 2022 Oct;
165(1):79-91.
PMID: 36215093
In Brief: Oocyte quality remains the most important and unsolved issue in reproduction. Our data show that multidrug resistance transporters and oocyte mitochondria are involved in determining oocyte quality in...
3.
Mehregan A, Ardestani G, Akizawa H, Carvacho I, Fissore R
J Cell Sci
. 2021 Jul;
134(13).
PMID: 34313315
Ca2+ influx during oocyte maturation and after sperm entry is necessary to fill the internal Ca2+ stores and for complete egg activation. We knocked out the transient receptor potential vanilloid...
4.
Aguila L, Felmer R, Arias M, Navarrete F, Martin-Hidalgo D, Lee H, et al.
Reproduction
. 2017 Jul;
154(3):307-318.
PMID: 28751536
The efficiency of intracytoplasmic sperm injection (ICSI) in the bovine is low compared to other species. It is unknown whether defective oocyte activation and/or sperm head decondensation limit the success...
5.
Hachem A, Godwin J, Ruas M, Lee H, Ferrer Buitrago M, Ardestani G, et al.
Development
. 2017 Jul;
144(16):2914-2924.
PMID: 28694258
Activation of the egg by the sperm is the first, vital stage of embryogenesis. The sperm protein PLCζ has been proposed as the physiological agent that triggers the Ca oscillations...
6.
Escoffier J, Lee H, Yassine S, Zouari R, Martinez G, Karaouzene T, et al.
Hum Mol Genet
. 2016 Jan;
25(5):878-91.
PMID: 26721930
In mammals, sperm-oocyte fusion initiates Ca(2+) oscillations leading to a series of events called oocyte activation, which is the first stage of embryo development. Ca(2+) signaling is elicited by the...
7.
Kornbluth S, Fissore R
Cold Spring Harb Perspect Biol
. 2015 Oct;
7(10):a006064.
PMID: 26430215
Vertebrate reproduction requires a myriad of precisely orchestrated events-in particular, the maternal production of oocytes, the paternal production of sperm, successful fertilization, and initiation of early embryonic cell divisions. These...
8.
Chithiwala Z, Lee H, Hill D, Jellerette-Nolan T, Fissore R, Grow D, et al.
J Assist Reprod Genet
. 2015 Jul;
32(9):1415-9.
PMID: 26174123
Purpose: The purpose of this study is to describe impaired oocyte fertilization from phospholipase C-zeta (PLC-ζ) deficiency in normal-appearing sperm that was successfully treated using calcium (Ca(2+)) ionophore with intracytoplasmic...
9.
Escoffier J, Yassine S, Lee H, Martinez G, Delaroche J, Coutton C, et al.
Mol Hum Reprod
. 2014 Oct;
21(2):157-68.
PMID: 25354701
We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia (70%) and described that Dpy19l2 knockout (KO) mice faithfully reproduce the human phenotype of globozoospermia making...
10.
Yassine S, Escoffier J, Martinez G, Coutton C, Karaouzene T, Zouari R, et al.
Mol Hum Reprod
. 2014 Oct;
21(2):169-85.
PMID: 25354700
We recently identified the DPY19L2 gene as the main genetic cause of human globozoospermia. Non-genetically characterized cases of globozoospermia were associated with DNA alterations, suggesting that DPY19L2-dependent globozoospermia may be...