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Rafael Dariolli

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Citations 369
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Recent Articles
21.
Varshneya M, Irurzun-Arana I, Campana C, Dariolli R, Gutierrez A, Pullinger T, et al.
medRxiv . 2020 Jun; PMID: 32511528
Many drugs that have been proposed for treatment of COVID-19 are reported to cause cardiac adverse events, including ventricular arrhythmias. In order to properly weigh risks against potential benefits, particularly...
22.
Arruda-Junior D, Martins F, Salles T, Jensen L, Dariolli R, Antonio E, et al.
Clin Sci (Lond) . 2020 May; 134(9):1081-1094. PMID: 32352510
The relationship between disturbances in glucose homeostasis and heart failure (HF) progression is bidirectional. However, the mechanisms by which HF intrinsically impairs glucose homeostasis remain unknown. The present study tested...
23.
Sanches Santos Rizzo Zuttion M, Camara D, Dariolli R, Takimura C, Wenceslau C, Kerkis I
Tissue Cell . 2019 May; 58:51-60. PMID: 31133246
Tissue-specific adult stem cells (ASC) are heterogeneous and characterized by a mix of progenitor cells that produce cells at various stages of differentiation, and ultimately different terminally differentiated cells. Understanding...
24.
Venturini G, Malagrino P, Padilha K, Tanaka L, Laurindo F, Dariolli R, et al.
Am J Physiol Cell Physiol . 2019 May; 317(2):C326-C338. PMID: 31067084
Atherosclerotic plaque development is closely associated with the hemodynamic forces applied to endothelial cells (ECs). Among these, shear stress (SS) plays a key role in disease development since changes in...
25.
Beraldo J, Benetti A, Borges-Junior F, Arruda-Junior D, Martins F, Jensen L, et al.
Int J Mol Sci . 2019 Apr; 20(8). PMID: 31010001
Dipeptidyl peptidase IV (DPPIV) inhibitors are antidiabetic agents that exert renoprotective actions independently of glucose lowering. Cardiac dysfunction is one of the main outcomes of chronic kidney disease (CKD); however,...
26.
Alves J, Martins A, Lameu C, Glaser T, Boukli N, Bassaneze V, et al.
Stem Cell Rev Rep . 2018 Oct; 15(1):48-58. PMID: 30338498
The bioactive peptide bradykinin obtained from cleavage of precursor kininogens activates the kinin-B2 receptor functioning in induction of inflammation and vasodilatation. In addition, bradykinin participates in kidney and cardiovascular development...
27.
Jensen L, Neri E, Bassaneze V, de Almeida Oliveira N, Dariolli R, Turaca L, et al.
J Cell Physiol . 2017 Dec; 233(7):5420-5430. PMID: 29219187
Neonatal cardiomyocytes are instrumental for disease modeling, but the effects of different cell extraction methods on basic cell biological processes remain poorly understood. We assessed the influence of two popular...
28.
Dariolli R, Naghetini M, Marques E, Takimura C, Jensen L, Kiers B, et al.
PLoS One . 2017 Apr; 12(4):e0176412. PMID: 28448588
Cell therapy repair strategies using adult mesenchymal stromal cells have shown promising evidence to prevent cardiac deterioration in rodents even in the absence of robust differentiation of the cells into...
29.
Steichen C, Si-Tayeb K, Wulkan F, Crestani T, Rosas G, Dariolli R, et al.
Curr Protoc Hum Genet . 2017 Jan; 92:21.7.1-21.7.22. PMID: 28075482
Human induced pluripotent stem (hiPS) cell technology has already revolutionized some aspects of fundamental and applied research such as study of disease mechanisms and pharmacology screening. The first clinical trial...
30.
Arruda-Junior D, Martins F, Dariolli R, Jensen L, Antonio E, Dos Santos L, et al.
Front Physiol . 2016 Jul; 7:293. PMID: 27462276
Circulating dipeptidyl peptidase IV (DPPIV) activity is associated with worse cardiovascular outcomes in humans and experimental heart failure (HF) models, suggesting that DPPIV may play a role in the pathophysiology...