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Radoslav Goldman

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Articles 85
Citations 1730
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Recent Articles
1.
Wang Z, Benicky J, Mukherjee P, Laing J, Xu Y, Pagadala V, et al.
Glycobiology . 2025 Mar; 35(4). PMID: 40044126
Heparan sulfate 6-endosulfatases (SULFs) remove 6-O-sulfo groups from heparan sulfate polysaccharide chains. SULFs modify the functions of heparan sulfate and contribute to the development of cancers, organ development and endothelial...
2.
Panigrahi A, Hunt A, Assis D, Willetts M, Kallakury B, Davidson B, et al.
bioRxiv . 2024 Aug; PMID: 39149249
We employed laser microdissection to selectively harvest tumor cells and stroma from the microenvironment of formalin-fixed, paraffin-embedded head and neck squamous cell carcinoma (HNSCC) tissues. The captured HNSCC tissue fractions...
3.
Panigrahi A, Benicky J, Aljuhani R, Mukherjee P, Novakova Z, Barinka C, et al.
Mol Cell Proteomics . 2024 Jun; 23(7):100793. PMID: 38825040
Human extracellular 6-O-endosulfatases Sulf-1 and Sulf-2 are the only enzymes that post-synthetically alter the 6-O sulfation of heparan sulfate proteoglycans (HSPG), which regulates interactions of HSPG with many proteins. Oncogenicity...
4.
Mukherjee P, Zhou X, Galli S, Davidson B, Zhang L, Ahn J, et al.
Int J Mol Sci . 2024 May; 25(9). PMID: 38732216
Aspartate β-hydroxylase (ASPH) is a protein associated with malignancy in a wide range of tumors. We hypothesize that inhibition of ASPH activity could have anti-tumor properties in patients with head...
5.
Panigrahi A, Benicky J, Aljuhani R, Mukherjee P, Novakova Z, Barinka C, et al.
bioRxiv . 2024 Jan; PMID: 38187586
Human extracellular 6--endosulfatases Sulf-1 and Sulf-2 are the only enzymes that post-synthetically alter the 6- sulfation of heparan sulfate proteoglycans (HSPG), which regulates interactions of HSPG with many proteins. Oncogenicity...
6.
Mukherjee P, Zhou X, Benicky J, Panigrahi A, Aljuhani R, Liu J, et al.
Cancers (Basel) . 2023 Nov; 15(21). PMID: 37958342
Local invasiveness of head and neck squamous cell carcinoma (HNSCC) is a complex phenomenon supported by interaction of the cancer cells with the tumor microenvironment (TME). We and others have...
7.
Campos D, Girgis M, Yang Q, Zong G, Goldman R, Wang L, et al.
Anal Chem . 2023 Jun; 95(27):10145-10148. PMID: 37382290
Mass spectrometry (MS) can unlock crucial insights into the intricate world of glycosylation analysis. Despite its immense potential, the qualitative and quantitative analysis of isobaric glycopeptide structures remains one of...
8.
Campos D, Girgis M, Yang Q, Zong G, Goldman R, Wang L, et al.
bioRxiv . 2023 Jun; PMID: 37292769
Graphical Abstract:
9.
Benicky J, Sanda M, Panigrahi A, Liu J, Wang Z, Pagadala V, et al.
Glycobiology . 2023 Apr; 33(5):384-395. PMID: 37052463
Sulf-2 is an extracellular heparan 6-O-endosulfatase involved in the postsynthetic editing of heparan sulfate (HS), which regulates many important biological processes. The activity of the Sulf-2 and its substrate specificity...
10.
Sanda M, Yang Q, Zong G, Chen H, Zheng Z, Dhani H, et al.
J Proteome Res . 2023 Feb; 22(4):1138-1147. PMID: 36763792
Targeted quantification of proteins is a standard methodology with broad utility, but targeted quantification of glycoproteins has not reached its full potential. The lack of optimized workflows and isotopically labeled...