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Radhika Kini

Explore the profile of Radhika Kini including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 410
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Recent Articles
1.
Subramanian M, Kini R, Madasu M, Ohta A, Nowak M, Exley M, et al.
Eur J Immunol . 2014 Jan; 44(4):1119-29. PMID: 24448964
Extracellular adenosine regulates inflammatory responses via the A2A adenosine receptor (A2AR). A2AR deficiency results in much exaggerated acute hepatitis, indicating nonredundancy of adenosine-A2AR pathway in inhibiting immune activation. To identify...
2.
Ohta A, Madasu M, Subramanian M, Kini R, Jones G, Chouker A, et al.
Int Immunol . 2013 Oct; 26(2):83-91. PMID: 24150242
Tissue hypoxia plays a key role in establishing an immunosuppressive environment in vivo by, among other effects, increasing the level of extracellular adenosine, which then signals through A2A adenosine receptor...
3.
Waly M, Hornig M, Trivedi M, Hodgson N, Kini R, Ohta A, et al.
Autism Res Treat . 2012 Aug; 2012:190930. PMID: 22934169
Although autism is first and foremost a disorder of the central nervous system, comorbid dysfunction of the gastrointestinal (GI) and immune systems is common, suggesting that all three systems may...
4.
Ohta A, Kini R, Ohta A, Subramanian M, Madasu M, Sitkovsky M
Front Immunol . 2012 Jul; 3:190. PMID: 22783261
The A2A adenosine receptor (A2AR)-mediated immunosuppression is firmly implicated in the life-saving down-regulation of collateral tissue damage during the anti-pathogen immune response and in highly undesirable protection of cancerous tissues...
5.
Ohta A, Diwanji R, Kini R, Subramanian M, Ohta A, Sitkovsky M
Front Immunol . 2012 May; 2:27. PMID: 22566817
Activation of immune cells is under control of immunological and physiological regulatory mechanisms to ensure adequate destruction of pathogens with the minimum collateral damage to "innocent" bystander cells. The concept...
6.
Ohta A, Ohta A, Madasu M, Kini R, Subramanian M, Goel N, et al.
J Immunol . 2009 Oct; 183(9):5487-93. PMID: 19843934
Immunosuppressive signaling via the A2A adenosine receptor (A2AR) provokes a mechanism that protects inflamed tissues from excessive damage by immune cells. This mechanism is desirable not only for preventing uncontrolled...