Rachele Rigano
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Explore the profile of Rachele Rigano including associated specialties, affiliations and a list of published articles.
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44
Citations
836
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Recent Articles
1.
Profumo E, Buttari B, Tosti M, Salvati B, Capoano R, Rigano R
Int J Immunopathol Pharmacol
. 2023 Jul;
37:3946320231160411.
PMID: 37478026
Objective: Carotid atherosclerosis, a major cause of ischemic cerebrovascular events, is characterized by a pro-inflammatory and pro-oxidant vascular microenvironment. The current risk score models based on traditional risk factors for...
2.
Caprari P, Profumo E, Massimi S, Buttari B, Rigano R, Regine V, et al.
Front Mol Biosci
. 2023 Jan;
9:1108896.
PMID: 36699704
The rheological properties of blood play an important role in regulating blood flow in micro and macro circulation. In thalassemia syndromes red blood cells exhibit altered hemodynamic properties that facilitate...
3.
Saha S, Profumo E, Togna A, Rigano R, Saso L, Buttari B
Oxid Med Cell Longev
. 2020 Oct;
2020:1232816.
PMID: 33062133
Macrophage activation and polarization play a central role in atherosclerotic plaque fate. The M1/M2 activation phenotypes represent two profiles of the macrophage polarization state. During atherosclerosis regression or stabilization, macrophages...
4.
Buttari B, Profumo E, Caprari P, Massimi S, Sorrentino F, Maffei L, et al.
Ann Hematol
. 2020 Aug;
99(10):2265-2277.
PMID: 32803313
β-Thalassemia is an inherited single gene disorder related to reduced synthesis of the β-globin chain of hemoglobin. Patients with β-thalassemia present variable clinical severity ranging from asymptomatic trait to severe...
5.
Buttari B, Profumo E, Capozzi A, Saso L, Sorice M, Rigano R
Crit Rev Clin Lab Sci
. 2019 Aug;
56(8):511-525.
PMID: 31448653
Antiphospholipid antibody syndrome (APS) is a systemic autoimmune disease characterized by arterial and venous thrombosis and/or pregnancy morbidity. The incidence is around five new cases/100,000 persons per year and the...
6.
Profumo E, Buttari B, Tinaburri L, DArcangelo D, Sorice M, Capozzi A, et al.
Oxid Med Cell Longev
. 2018 Jun;
2018:2373167.
PMID: 29849874
We have previously demonstrated that human heat shock protein 90 (HSP90), an intracellular self protein, is the target of cellular and humoral autoimmune responses in patients with carotid atherosclerosis. In...
7.
Profumo E, Buttari B, DArcangelo D, Tinaburri L, Dettori M, Fabbri D, et al.
Oxid Med Cell Longev
. 2017 Jan;
2016:1246485.
PMID: 28050226
Atherosclerosis is characterized by endothelial dysfunction, mainly induced by inflammation and oxidative stress. Increased reactive oxygen species (ROS) production together with increased adhesion molecules and thrombogenic tissue factor (TF) expression...
8.
Buttari B, Profumo E, Rigano R
Biomed Res Int
. 2015 Feb;
2015:616834.
PMID: 25722984
Atherosclerosis is a chronic multifactorial disease of the arterial wall characterized by inflammation, oxidative stress, and immune system activation. Evidence exists on a pathogenic role of oxidized red blood cells...
9.
Profumo E, Buttari B, Saso L, Rigano R
Curr Top Med Chem
. 2014 Dec;
14(22):2542-51.
PMID: 25478882
Cardiovascular diseases, which are the leading cause of mortality in the Western World, are closely associated with atherosclerosis development. Atherosclerosis is a chronic multifactorial disease of the arterial wall characterized...
10.
Buttari B, Profumo E, Segoni L, DArcangelo D, Rossi S, Facchiano F, et al.
Oxid Med Cell Longev
. 2014 Jun;
2014:257543.
PMID: 24895526
the proinflammatory M1 subset and the anti-inflammatory M2 one. 7-oxo-cholesterol, the most abundant cholesterol autoxidation product within atherosclerotic plaque, is able to skew the M1/M2 balance towards a proinflammatory profile....