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Rachael A Mansbach

Explore the profile of Rachael A Mansbach including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 300
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Recent Articles
1.
Mai M, Zazubovich V, Mansbach R
J Phys Chem B . 2024 Feb; 128(6):1371-1384. PMID: 38299975
Reversible light and thermally induced spectral shifts are universally observed in a wide variety of pigment-protein complexes at temperatures ranging from cryogenic to ambient. In this paper, we employed large-scale...
2.
Mansbach R, Patel L, Watson N, Kubicek-Sutherland J, Gnanakaran S
J Phys Chem B . 2023 Feb; 127(8):1689-1703. PMID: 36791259
Short, cysteine-rich peptides can exist in stable or metastable structural ensembles due to the number of possible patterns of formation of their disulfide bonds. One interesting subset of this peptide...
3.
Nguyen K, Chakraborty S, Mansbach R, Korber B, Gnanakaran S
Viruses . 2021 Jun; 13(5). PMID: 34067878
COVID-19 is a highly infectious respiratory disease caused by the novel coronavirus SARS-CoV-2. It has become a global pandemic and its frequent mutations may pose new challenges for vaccine design....
4.
Mansbach R, Chakraborty S, Nguyen K, Montefiori D, Korber B, Gnanakaran S
Sci Adv . 2021 Apr; 7(16). PMID: 33863729
The COVID-19 (coronavirus disease 2019) pandemic underwent a rapid transition with the emergence of a dominant viral variant (from the "D-form" to the "G-form") that carried an amino acid substitution...
5.
Lindsay R, Mansbach R, Gnanakaran S, Shen T
Biophys Chem . 2021 Feb; 271:106552. PMID: 33581430
The conformational ensemble of intrinsically disordered proteins, such as α-synuclein, are responsible for their function and malfunction. Misfolding of α-synuclein can lead to neurodegenerative diseases, and the ability to study...
6.
Mansbach R, Chakraborty S, Nguyen K, Montefiori D, Korber B, Gnanakaran S
bioRxiv . 2020 Aug; PMID: 32743581
The COVID-19 pandemic underwent a rapid transition with the emergence of a SARS-CoV-2 variant that carried the amino acid substitution D614G in the Spike protein that became globally prevalent. The...
7.
Mansbach R, Leus I, Mehla J, Lopez C, Walker J, Rybenkov V, et al.
J Chem Inf Model . 2020 May; 60(6):2838-2847. PMID: 32453589
Drug discovery faces a crisis. The industry has used up the "obvious" space in which to find novel drugs for biomedical applications, and productivity is declining. One strategy to combat...
8.
Mansbach R, Chakraborty S, Travers T, Gnanakaran S
Mar Drugs . 2020 May; 18(5). PMID: 32422972
Conotoxins are short, cysteine-rich peptides of great interest as novel therapeutic leads and of great concern as lethal biological agents due to their high affinity and specificity for various receptors...
9.
Shmilovich K, Mansbach R, Sidky H, Dunne O, Panda S, Tovar J, et al.
J Phys Chem B . 2020 Mar; 124(19):3873-3891. PMID: 32180410
Electronically active organic molecules have demonstrated great promise as novel soft materials for energy harvesting and transport. Self-assembled nanoaggregates formed from π-conjugated oligopeptides composed of an aromatic core flanked by...
10.
Travers T, Kanagy W, Mansbach R, Jhamba E, Cleyrat C, Goldstein B, et al.
Mol Biol Cell . 2019 Jun; 30(17):2331-2347. PMID: 31216232
Syk/Zap70 family kinases are essential for signaling via multichain immune-recognition receptors such as tetrameric (αβγ2) FcεRI. Syk activation is generally attributed to binding of its tandem SH2 domains to dual...