R Y C Poon
Overview
Explore the profile of R Y C Poon including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
5
Citations
327
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Chen H, Huang S, Han X, Zhang J, Shan C, Tsang Y, et al.
Cell Death Dis
. 2014 Apr;
5:e1177.
PMID: 24743732
Many mitotic kinases are both critical for maintaining genome stability and are important targets for anticancer therapies. We provide evidence that SIK3 (salt-inducible kinase 3), an AMP-activated protein kinase-related kinase,...
2.
Marxer M, Ma H, Man W, Poon R
Oncogene
. 2013 Aug;
33(27):3550-60.
PMID: 23955083
A number of small-molecule inhibitors of Aurora kinases have been developed and are undergoing clinical trials for anti-cancer therapies. Different Aurora kinases, however, behave as very different targets: while inhibition...
3.
Chow J, Poon R
Oncogene
. 2012 Nov;
32(40):4778-88.
PMID: 23146904
Inhibition of cyclin-dependent kinase 1 (CDK1) by phosphorylation is a key regulatory mechanism for both the unperturbed cell cycle and the DNA damage checkpoint. Although both WEE1 and MYT1 can...
4.
Generation of an indestructible cyclin B1 by caspase-6-dependent cleavage during mitotic catastrophe
Chan Y, Chen Y, Poon R
Oncogene
. 2008 Sep;
28(2):170-83.
PMID: 18820706
Overriding the G(2) DNA damage checkpoint permits precocious entry into mitosis that ultimately leads to mitotic catastrophe. Mitotic catastrophe is manifested by an unscheduled activation of CDK1, caspase activation and...
5.
Yam C, Fung T, Poon R
Cell Mol Life Sci
. 2002 Oct;
59(8):1317-26.
PMID: 12363035
Cyclin A is particularly interesting among the cyclin family because it can activate two different cyclin-dependent kinases (CDKs) and functions in both S phase and mitosis. An embryonic form of...