R Webster West
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Explore the profile of R Webster West including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
56
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Recent Articles
1.
Piegorsch W, An L, Wickens A, West R, Pena E, Wu W
Environmetrics
. 2013 Sep;
24(3):143-157.
PMID: 24039461
An important objective in environmental risk assessment is estimation of minimum exposure levels, called Benchmark Doses (BMDs), that induce a pre-specified Benchmark Response (BMR) in a dose-response experiment. In such...
2.
West R, Piegorsch W, Pena E, An L, Wu W, Wickens A, et al.
Environmetrics
. 2013 Jun;
23(8):706-716.
PMID: 23794799
We study the popular benchmark dose (BMD) approach for estimation of low exposure levels in toxicological risk assessment, focusing on dose-response experiments with quantal data. In such settings, representations of...
3.
West R, Nitcheva D, Piegorsch W
Environ Ecol Stat
. 2010 Feb;
16(1):63-73.
PMID: 20160852
A primary objective in quantitative risk assessment is the characterization of risk which is defined to be the likelihood of an adverse effect caused by an environmental toxin or chemcial...
4.
Buckley B, Piegorsch W, West R
Environ Ecol Stat
. 2010 Feb;
16(1):53-62.
PMID: 20160851
In modern environmental risk analysis, inferences are often desired on those low dose levels at which a fixed benchmark risk is achieved. In this paper, we study the use of...
5.
Nitcheva D, Piegorsch W, West R
Regul Toxicol Pharmacol
. 2007 May;
48(2):135-47.
PMID: 17490794
We explore how well a statistical multistage model describes dose-response patterns in laboratory animal carcinogenicity experiments from a large database of quantal response data. The data are collected from the...
6.
Piegorsch W, West R
Risk Anal
. 2005 Nov;
25(4):913-20.
PMID: 16268938
We discuss the issue of using benchmark doses for quantifying (excess) risk associated with exposure to environmental hazards. The paradigm of low-dose risk estimation in dose-response modeling is used as...
7.
Modeling the simple epidemic with deterministic differential equations and random initial conditions
Kegan B, West R
Math Biosci
. 2005 May;
195(2):179-93.
PMID: 15907949
In a simple epidemic the only transition in the population is from susceptible to infected and the total population size is fixed for all time. This paper investigates the effect...
8.
Modeling the simple epidemic with deterministic differential equations and random initial conditions
Kegan B, West R
Math Biosci
. 2005 Apr;
194(2):217-31.
PMID: 15854677
In a simple epidemic the only transition in the population is from susceptible to infected and the total population size is fixed for all time. This paper investigates the effect...
9.
Nitcheva D, Piegorsch W, West R, Kodell R
Biometrics
. 2005 Mar;
61(1):277-86.
PMID: 15737104
A primary objective in quantitative risk or safety assessment is characterization of the severity and likelihood of an adverse effect caused by a chemical toxin or pharmaceutical agent. In many...
10.
Piegorsch W, West R, Pan W, Kodell R
J Biopharm Stat
. 2005 Feb;
15(1):17-31.
PMID: 15702602
We study the use of simultaneous confidence bounds for making low-dose inferences in quantitative risk analysis. Confidence limits are constructed for outcomes measured on a continuous scale, assuming a simple...