R W Giese
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Explore the profile of R W Giese including associated specialties, affiliations and a list of published articles.
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82
Citations
89
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Recent Articles
1.
Cecchini D, Ehrat M, Giese R
J Am Chem Soc
. 2012 Jan;
108(24):7841-3.
PMID: 22283301
No abstract available.
2.
Giese R
J Chromatogr A
. 2000 Oct;
892(1-2):329-46.
PMID: 11045497
Electron-capture (EC) is a sensitive and selective ionization technique for mass spectrometry (MS). In the most familiar form of EC, a susceptible analyte (electrophore) is detected after eluting from a...
3.
Bocek P, Vespalec R, Giese R
Anal Chem
. 2000 Sep;
72(17):586A-595A.
PMID: 10994948
No abstract available.
4.
Lu R, Giese R
Anal Chem
. 2000 Apr;
72(8):1798-801.
PMID: 10784144
Acetamide, 2-amino-N-[[3,5-bis(trifluoromethyl)phenyl]-methyl]-N-methyl-, monohydrochloride, which we have named AMACE1, was synthesized in three steps starting from N-tritylglycine. AMACE1 was coupled via its primary amine group (pKa 8.2) under aqueous conditions to...
5.
Lan Z, Wang P, Giese R
Rapid Commun Mass Spectrom
. 1999 Jul;
13(14):1454-7.
PMID: 10407338
The four major deoxynucleotides of DNA, and adduct mixtures resulting from separate reactions of 5'-dAMP and 5'-dGMP with benzo[a]pyrene diolepoxide (BPDE), were analyzed by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS)...
6.
Lan Z, Qian X, Giese R
J Chromatogr A
. 1999 Mar;
831(2):325-30.
PMID: 10070766
We are studying dye-imidazole conjugates ("IMI dyes") as reagents for labeling phosphomonoesters such as nucleotides. Previously we have employed a BODIPY dye in our IMI reagents, and analyzed the labeled...
7.
Xu L, Huang Y, Giese R
J Mass Spectrom
. 1998 Aug;
33(7):615-20.
PMID: 9692245
Towards the goal of finding new ketone electrophores suitable as molecular labels for electrophoric release tags, pentafluorophenoxyacetone (1) and pentafluorobenzyloxyacetone (2) were prepared. Both ketones were evaluated by electron capture...
8.
Wang P, Giese R
J Chromatogr A
. 1998 Jul;
809(1-2):211-8.
PMID: 9677715
Previously we reported than BO-IMI, a reagent which contains a BODIPY fluorophore linked to an imidazole group, can be used to covalently label a phosphomonoester in a single step under...
9.
Wang Z, Bian N, Qian X, Giese R
J Chromatogr A
. 1998 Jun;
806(1):93-5.
PMID: 9639882
Difficulties were encountered in labeling 5'-aminoalkyl DNA oligomers with glycolketo electrophore N-hydroxysuccinimide esters in aqueous sodium bicarbonate (a common base for this purpose), followed by C18-silica reversed-phase high-performance liquid chromatography...
10.
Xu L, Bian N, Wang Z, Pillai S, Magiera D, Murugaiah V, et al.
Anal Chem
. 1997 Sep;
69(17):3595-602.
PMID: 9286165
Toward a goal of dideoxy sequencing DNA utilizing electrophore labels, we prepared four electrophore-labeled DNA oligonucleotide primers. Each primer has a different electrophore and DNA sequence but a common glycol...