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R Toomik

Explore the profile of R Toomik including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 33
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Recent Articles
1.
Loog M, Toomik R, Sak K, Muszynska G, Jarv J, Ek P
Eur J Biochem . 2000 Jan; 267(2):337-43. PMID: 10632703
Ca2+-dependent protein kinase (CDPK-1) was purified from maize seedlings, and its substrate specificity studied using a set of synthetic peptides derived from the phosphorylatable sequence RVLSRLHS15VRER of maize sucrose synthase...
2.
Janson I, Toomik R, OFarrell F, Ek P
Biochem Biophys Res Commun . 1998 Jun; 247(2):447-51. PMID: 9642148
The ER retention of lumenal proteins is achieved by a process which involves binding of escaped proteins via the C-terminal KDEL-tags to a KDEL receptor (erd2 receptor) in a post-ER...
3.
Ek P, Toomik R, Eriksson S, Frithz G, Ronquist G, Engstrom L
J Intern Med . 1998 Jun; 243(4):299-305. PMID: 9627144
Objectives: Increased protein kinase C activity has been reported in erythrocytes from patients with primary hypertension and also from hypertensive rats. In this phenomenological study, we investigated whether a possible...
4.
Edlund M, Wikstrom K, Toomik R, Ek P, Obrink B
FEBS Lett . 1998 Apr; 425(1):166-70. PMID: 9541029
C-CAM is a ubiquitously expressed cell adhesion molecule belonging to the carcinoembryonic antigen family. Two co-expressed isoforms, C-CAM-L and C-CAM-S, are known, having different cytoplasmic domains both of which can...
5.
Toomik R, Ek P
Biochem J . 1997 Mar; 322 ( Pt 2):455-60. PMID: 9065763
Protein kinases exhibit substrate specificities that are often primarily determined by the amino acids around the phosphorylation sites. Peptides corresponding to protein kinase C phosphorylation sites in several different proteins...
6.
Toomik R, Edlund M, Ek P, Obrink B, Engstrom L
Pept Res . 1996 Jan; 9(1):6-11. PMID: 8727478
Sets of peptides with defined sequences, each on a separate spot, were synthesized simultaneously on continuous cellulose membranes (SPOTs membranes), which were originally designed for epitope studies. The applicability of...
7.
Toomik R, Eller M, Ekman P, Ragnarsson U, Engstrom L
Biochem Biophys Res Commun . 1994 May; 200(3):1564-9. PMID: 8185612
A set of diastereomeric peptides RRRDDDSDDD each with a corresponding D-amino acid residue successively in every position (except the arginines) was tested as substrates for casein kinase II. It was...
8.
Eller M, Jarv J, Toomik R, Ragnarsson U, Ekman P, Engstrom L
J Biochem . 1993 Aug; 114(2):177-80. PMID: 8262896
A set of stereoisomeric nonapeptides KRPSQRAKY with one, two, or all L-amino acid residues replaced by the corresponding D-amino acids, and two analogs with L- and D-threonine instead of serine,...
9.
Toomik R, Ekman P, Eller M, Jarv J, Zaitsev D, Myasoedov N, et al.
Anal Biochem . 1993 Mar; 209(2):348-53. PMID: 8470809
The recently described synthesis of ferric adsorbent paper has made possible the modification of protein kinase assays. The adsorbent contains ferric chelate groups, which are responsible for the binding of...
10.
Toomik R, Toomik P
Prep Biochem . 1992 Sep; 22(3-4):183-97. PMID: 1287648
A procedure for the synthesis of a selective adsorbent for phosphate-containing biomolecules is described. The sorbent is based on Whatman chromatography paper, which is activated with epichlorohydrine, followed by the...