R Thomas Lumbers
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Explore the profile of R Thomas Lumbers including associated specialties, affiliations and a list of published articles.
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45
Citations
1754
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Recent Articles
1.
Henry A, Mo X, Finan C, Chaffin M, Speed D, Issa H, et al.
Nat Genet
. 2025 Mar;
PMID: 40038546
Heart failure (HF) is a major contributor to global morbidity and mortality. While distinct clinical subtypes, defined by etiology and left ventricular ejection fraction, are well recognized, their genetic determinants...
2.
Linner E, Czuba T, Gidlof O, Lundgren J, Bollano E, Hellberg M, et al.
Sci Rep
. 2025 Feb;
15(1):4306.
PMID: 39910139
The genetic contributions to early onset heart failure (HF) are incompletely understood. Genetic testing in advanced HF patients undergoing heart transplantation (HTx) may yield clinical benefits, but data is limited....
3.
Van Gelder I, Rienstra M, Bunting K, Casado-Arroyo R, Caso V, Crijns H, et al.
G Ital Cardiol (Rome)
. 2025 Feb;
26(2 Suppl 1):e1-e104.
PMID: 39898766
No abstract available.
4.
Rienstra M, Tzeis S, Bunting K, Caso V, Crijns H, De Potter T, et al.
Europace
. 2024 Dec;
26(12).
PMID: 39716733
Atrial fibrillation (AF) remains the most common cardiac arrhythmia worldwide and is associated with significant morbidity and mortality. The European Society of Cardiology (ESC)/European Association for Cardio-Thoracic Surgery (EACTS) have...
5.
Allara E, Bell S, Smith R, Keene S, Gill D, Gaziano L, et al.
Commun Biol
. 2024 Dec;
7(1):1631.
PMID: 39643614
Iron homoeostasis is tightly regulated, with hepcidin and soluble transferrin receptor (sTfR) playing significant roles. However, the genetic determinants of these traits and the biomedical consequences of iron homoeostasis variation...
6.
Jurgens S, Ramo J, Kramarenko D, Wijdeveld L, Haas J, Chaffin M, et al.
Nat Genet
. 2024 Dec;
56(12):2843.
PMID: 39633063
No abstract available.
7.
Jurgens S, Ramo J, Kramarenko D, Wijdeveld L, Haas J, Chaffin M, et al.
Nat Genet
. 2024 Nov;
56(12):2636-2645.
PMID: 39572784
Dilated cardiomyopathy (DCM) is a heart muscle disease that represents an important cause of morbidity and mortality, yet causal mechanisms remain largely elusive. Here, we perform a large-scale genome-wide association...
8.
Zheng S, Henry A, Cannie D, Lee M, Miller D, McGurk K, et al.
Nat Genet
. 2024 Nov;
56(12):2646-2658.
PMID: 39572783
Dilated cardiomyopathy (DCM) is a leading cause of heart failure and cardiac transplantation. We report a genome-wide association study and multi-trait analysis of DCM (14,256 cases) and three left ventricular...
9.
McGurk K, Qiao M, Zheng S, Sau A, Henry A, Ribeiro A, et al.
Nat Cardiovasc Res
. 2024 Nov;
3(12):1503-1515.
PMID: 39567769
Cardiac trabeculae form a network of muscular strands that line the inner surfaces of the heart. Their development depends on multiscale morphogenetic processes and, while highly conserved across vertebrate evolution,...
10.
Champsi A, Mobley A, Subramanian A, Nirantharakumar K, Wang X, Shukla D, et al.
Eur Heart J
. 2024 Sep;
45(36):3707-3717.
PMID: 39217497
Background And Aims: The role of gender in decision-making for oral anticoagulation in patients with atrial fibrillation (AF) remains controversial. Methods: The population cohort study used electronic healthcare records of...