R Thomas Boyd
Overview
Explore the profile of R Thomas Boyd including associated specialties, affiliations and a list of published articles.
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17
Citations
656
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Recent Articles
1.
Borniger J, Don R, Zhang N, Boyd R, Nelson R
Am J Physiol Regul Integr Comp Physiol
. 2017 Jun;
313(3):R280-R289.
PMID: 28637659
The long-term consequences of early life nicotine exposure are poorly defined. Approximately 8-10% of women report smoking during pregnancy, and this may promote aberrant development in the offspring. To this...
2.
Henderson B, Gonzalez-Cestari T, Yi B, Pavlovicz R, Boyd R, Li C, et al.
ACS Chem Neurosci
. 2012 Sep;
3(9):682-92.
PMID: 23019495
Neuronal nicotinic receptors (nAChRs) have been implicated in several diseases and disorders such as autism spectrum disorders, Alzheimer's disease, Parkinson's disease, epilepsy, and nicotine addiction. To understand the role of...
3.
Papke R, Ono F, Stokes C, Urban J, Boyd R
Biochem Pharmacol
. 2012 May;
84(3):352-65.
PMID: 22580045
Zebrafish (Danio rerio) have been used to study multiple effects of nicotine, for example on cognition, locomotion, and stress responses, relying on the assumption that pharmacological tools will operate similarly...
4.
Pavlovicz R, Henderson B, Bonnell A, Boyd R, McKay D, Li C
PLoS One
. 2011 Sep;
6(9):e24949.
PMID: 21949802
Acetylcholine-based neurotransmission is regulated by cationic, ligand-gated ion channels called nicotinic acetylcholine receptors (nAChRs). These receptors have been linked to numerous neurological diseases and disorders such as Alzheimer's disease, Parkinson's...
5.
Potaros T, Phornchirasilp S, McKay S, Gonzalez-Cestari T, Boyd R, McKay D
Neurosci Lett
. 2010 Dec;
489(2):105-9.
PMID: 21138757
Evidence exists supporting the involvement of adenomatous polyposis coli (APC) protein in the assembly of neuronal nicotinic acetylcholine receptors (nAChRs) in the postsynaptic complex. In the following studies, the effects...
6.
Henderson B, Pavlovicz R, Allen J, Gonzalez-Cestari T, Orac C, Bonnell A, et al.
J Pharmacol Exp Ther
. 2010 Jun;
334(3):761-74.
PMID: 20551292
Allosteric modulation of neuronal nicotinic acetylcholine receptors (nAChRs) is considered to be one of the most promising approaches for therapeutics. We have previously reported on the pharmacological activity of several...
7.
Mishra N, Rir-Sima-Ah J, Boyd R, Singh S, Gundavarapu S, Langley R, et al.
J Immunol
. 2010 May;
185(1):588-96.
PMID: 20505147
Smokers are less likely to develop some inflammatory and allergic diseases. In Brown-Norway rats, nicotine inhibits several parameters of allergic asthma, including the production of Th2 cytokines and the cysteinyl...
8.
Ackerman K, Nakkula R, Zirger J, Beattie C, Boyd R
Dev Dyn
. 2009 Mar;
238(4):980-92.
PMID: 19301390
Acetylcholine plays an important role in regulation of nervous system development and function. We are developing zebrafish (Danio rerio) as a model system to study the role of specific neuronal...
9.
Gonzalez-Cestari T, Henderson B, Pavlovicz R, McKay S, El-Hajj R, Pulipaka A, et al.
J Pharmacol Exp Ther
. 2008 Nov;
328(2):504-15.
PMID: 18984653
Allosteric modulation of nAChRs is considered to be one of the most promising approaches for drug design targeting nicotinic acetylcholine receptors (nAChRs). We have reported previously on the pharmacological activity...
10.
Razani-Boroujerdi S, Boyd R, Davila-Garcia M, Nandi J, Mishra N, Singh S, et al.
J Immunol
. 2007 Aug;
179(5):2889-98.
PMID: 17709503
Acute and chronic effects of nicotine on the immune system are usually opposite; acute treatment stimulates while chronic nicotine suppresses immune and inflammatory responses. Nicotine acutely raises intracellular calcium ([Ca(2+)](i))...