R T Elder
Overview
Explore the profile of R T Elder including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
677
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Recent Articles
1.
Elder R, Yu M, Chen M, Zhu X, Yanagida M, Zhao Y
Virology
. 2001 Sep;
287(2):359-70.
PMID: 11531413
Viral protein R (Vpr) of human immunodeficiency virus type 1 induces G2 arrest in cells from distantly related eukaryotes including human and fission yeast through inhibitory phosphorylation of tyrosine 15...
2.
Zhao Y, Elder R
Front Biosci
. 2000 Dec;
5:D905-16.
PMID: 11102318
Increasing evidence suggests that HIV-1 viral protein R (Vpr) plays an important role in viral pathogenesis, as its functions are being linked to viral activation, suppression of human immune functions...
3.
Elder R, Yu M, Chen M, Edelson S, Zhao Y
Virus Res
. 2000 Aug;
68(2):161-73.
PMID: 10958988
HIV-1 Vpr induces cell cycle G2 arrest, morphological changes and cell death in human and fission yeast cells. The cellular targets for G2 arrest were expected to be the inhibitory...
4.
Chen M, Elder R, Yu M, OGorman M, Selig L, Benarous R, et al.
J Virol
. 1999 Mar;
73(4):3236-45.
PMID: 10074177
Cell cycle G2 arrest, nuclear localization, and cell death induced by human immunodeficiency virus type 1 Vpr were examined in fission yeast by using a panel of Vpr mutations that...
5.
Zhao Y, Elder R, Chen M, Cao J
Biotechniques
. 1998 Oct;
25(3):438-40, 442, 444.
PMID: 9762442
A pYZ series of fission yeast expression vectors, derivatives of the pREP series, was designed to allow positive identification of cloned gene insertion and fusion to the green fluorescent protein...
6.
Zhao Y, Yu M, Chen M, Elder R, Yamamoto A, Cao J
Virology
. 1998 Jul;
246(2):266-76.
PMID: 9657945
Expression of HIV-1 Vpr causes cell cycle G2 arrest, change in cell shape, and cell death over a large evolutionary distance ranging from human to yeast cells. As a step...
7.
Xu X, Williams J, Shen J, Gong H, Yin D, Blinder L, et al.
J Immunol
. 1998 Apr;
160(2):846-53.
PMID: 9551920
Intracellular pyrimidine nucleotides (PyN) can be synthesized de novo from glutamine, CO2, and ATP, or they can be salvaged from preformed pyrimidine nucleosides. The antiproliferative and immunosuppressive activities of brequinar...
8.
Elder R, Xu X, Williams J, Gong H, Finnegan A, Chong A
J Immunol
. 1997 Jul;
159(1):22-7.
PMID: 9200434
The immunosuppressive metabolite of leflunomide, A77 1726, inhibits the enzymatic activity of protein tyrosine kinases and of dihydro-orotic acid dehydrogenase, an enzyme involved in pyrimidine biosynthesis. Here murine CTLL cell...
9.
Houtteman S, Elder R
Mol Cell Biol
. 1993 Mar;
13(3):1489-96.
PMID: 8441392
Yeast autonomously replicating sequence (ARS) plasmids exhibit an unusual segregation pattern during mitosis. While the nucleus divides equally into mother and daughter cells, all copies of the ARS plasmid will...
10.
Buckingham L, Wang H, Elder R, McCarroll R, Slater M, Esposito R
Proc Natl Acad Sci U S A
. 1990 Dec;
87(23):9406-10.
PMID: 2123556
The SPO13 gene, required for meiosis I segregation in Saccharomyces cerevisiae, produces two developmentally regulated transcripts (1.0 and 1.4 kilobases) that differ in length at their 5' ends. The shorter...