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R Sinclair

Explore the profile of R Sinclair including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 172
Citations 1594
Followers 0
Related Specialties
Dermatology
Biochemistry
General Medicine
Top 10 Co-Authors
J Cassuto
J A Mumford
J Shapiro
A Goren
I Yamazaki
H D Zhou
J McCoy
L Powers
A Tosti
S Vano-Galvan
Published In
Br J Dermatol
J Eur Acad Dermatol Venereol
Biochemistry
Australas J Dermatol
In Vitro
Affiliations
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Recent Articles
1.
Patterns of clinical response in patients with alopecia areata treated with ritlecitinib in the ALLEGRO clinical development programme
King B, Mirmirani P, Lo Sicco K, Ramot Y, Sinclair R, Asfour L, et al.
J Eur Acad Dermatol Venereol . 2025 Feb; PMID: 39962358
Background: Ritlecitinib, an oral JAK3/TEC family kinase inhibitor, demonstrated efficacy over 48 weeks in patients with alopecia areata (AA) in the ALLEGRO phase 2b/3 study. Objectives: This post hoc analysis...
2.
Long-term safety and efficacy of ritlecitinib in adults and adolescents with alopecia areata and at least 25% scalp hair loss: Results from the ALLEGRO-LT phase 3, open-label study
Tziotzios C, Sinclair R, Lesiak A, Mehlis S, Kinoshita-Ise M, Tsianakas A, et al.
J Eur Acad Dermatol Venereol . 2025 Jan; PMID: 39846397
Background: ALLEGRO-LT is an ongoing, long-term, open-label, multicentre, phase 3 study of ritlecitinib in adults and adolescents with alopecia areata (AA). Objectives: To evaluate ritlecitinib safety and efficacy through Month...
3.
Long-term efficacy and safety of baricitinib in patients with severe alopecia areata: 104-week results from BRAVE-AA1 and BRAVE-AA2
Senna M, Mostaghimi A, Ohyama M, Sinclair R, Dutronc Y, Wu W, et al.
J Eur Acad Dermatol Venereol . 2024 Feb; 38(3):583-593. PMID: 38391212
Background: Efficacy of the Janus kinase (JAK) inhibitor baricitinib for severe alopecia areata (AA) continuously increased over 52 weeks in two Phase 3 trials. There are limited long-term data on...
4.
Incidence and prevalence of alopecia areata in the Australian primary care setting: A retrospective analysis of electronic health record data
Sinclair R, Eisman S, Song W, Heung B, Surian C, Lee C, et al.
Australas J Dermatol . 2023 Jul; 64(3):330-338. PMID: 37408523
Background: Alopecia areata (AA) is a common immune-mediated non-scarring hair loss, with a worldwide incidence between 0.57% and 3.8%. The incidence and prevalence of AA in the Australian general population...
5.
Phase 2 BELIEVE study part B: Efficacy and safety of rilzabrutinib for patients with pemphigus vulgaris
Murrell D, Patsatsi A, Stavropoulos P, Baum S, Zeeli T, Kern J, et al.
J Eur Acad Dermatol Venereol . 2022 Jun; PMID: 35686647
No abstract available.
6.
Alopecia areata: progress, but who pays?
Sinclair R
Br J Dermatol . 2021 Oct; 186(2):206-207. PMID: 34617588
No abstract available.
7.
Clinicopathological characteristics and treatment outcomes of fibrosing alopecia in a pattern distribution: A retrospective cohort study
Jerjen R, Pinczewski J, Sinclair R, Bhoyrul B
J Eur Acad Dermatol Venereol . 2021 Aug; 35(12):2440-2447. PMID: 34415628
Background: Fibrosing alopecia in a pattern distribution (FAPD) is a primary cicatricial alopecia considered a subtype of lichen planopilaris (LPP). Objective: The clinical and histopathological features, and treatment response of...
8.
Athena: Speciality Certificate Examination case for Paediatrics and Genetics: a case of brittle hair
Asfour L, Sinclair R
Clin Exp Dermatol . 2021 Jul; 47(7):1388-1390. PMID: 34309895
Genetic hair disorders can be an isolated phenomenon or part of a multisystem syndrome. Microscopic examination of scalp hair can provide useful information to aid diagnosis. This article describes several...
9.
Guidelines for clinical trials of frontal fibrosing alopecia: consensus recommendations from the International FFA Cooperative Group (IFFACG)
Olsen E, Harries M, Tosti A, Bergfeld W, Blume-Peytavi U, Callender V, et al.
Br J Dermatol . 2021 Jun; 185(6):1221-1231. PMID: 34105768
Background: Frontal fibrosing alopecia (FFA) has become one of the most common causes of cicatricial alopecia worldwide. However, there is a lack of clear aetiology and robust clinical trial evidence...
10.
Dual Orbital Degeneracy Lifting in a Strongly Correlated Electron System
Koch R, Sinclair R, McDonnell M, Yu R, Abeykoon M, Tucker M, et al.
Phys Rev Lett . 2021 May; 126(18):186402. PMID: 34018766
The local structure of NaTiSi_{2}O_{6} is examined across its Ti-dimerization orbital-assisted Peierls transition at 210 K. An atomic pair distribution function approach evidences local symmetry breaking preexisting far above the...