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R Scandurra

Explore the profile of R Scandurra including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 84
Citations 352
Followers 0
Related Specialties
Biochemistry
Endocrinology
Biology
Top 10 Co-Authors
L Politi
V Consalvi
D Cavallini
R Chiaraluce
G Polidoro
M de Rosa
S Dupre
P C Engel
D Di Cola
N Cerulli
Published In
Eur J Biochem
Acta Vitaminol Enzymol
Boll Soc Ital Biol Sper
Ital J Biochem
FEBS Lett
Affiliations
Soon will be listed here.
Recent Articles
1.
Chondroprotective activity of N-acetyl phenylalanine glucosamine derivative on knee joint structure and inflammation in a murine model of osteoarthritis
Veronesi F, Giavaresi G, Maglio M, Scotto dAbusco A, Politi L, Scandurra R, et al.
Osteoarthritis Cartilage . 2016 Nov; 25(4):589-599. PMID: 27836674
Objective: Osteoarthritis (OA), the most common chronic degenerative joint disease, is characterized by joint structure changes and inflammation, both mediated by the IκB kinase (IKK) signalosome complex. The ability of...
2.
The endocrine disruptor cadmium alters human osteoblast-like Saos-2 cells homeostasis in vitro by alteration of Wnt/β-catenin pathway and activation of caspases
Papa V, Bimonte V, Wannenes F, DAbusco A, Fittipaldi S, Scandurra R, et al.
J Endocrinol Invest . 2015 Sep; 38(12):1345-56. PMID: 26335301
Purpose: The pollutant Cadmium (Cd) is widespread in the environment and causes alterations of human health by acting as an endocrine disruptor. Bone tissue seems to be a crucial target...
3.
Graphitic carbon in a nanostructured titanium oxycarbide thin film to improve implant osseointegration
Zanoni R, Ioannidu C, Mazzola L, Politi L, Misiano C, Longo G, et al.
Mater Sci Eng C Mater Biol Appl . 2014 Dec; 46:409-16. PMID: 25492005
A nanostructured coating layer on titanium implants, able to improve their integration into bones and to protect against the harsh conditions of body fluids, was obtained by Ion Plating Plasma...
4.
Effect of glucosamine and its peptidyl-derivative on the production of extracellular matrix components by human primary chondrocytes
Stoppoloni D, Politi L, Leopizzi M, Gaetani S, Guazzo R, Basciani S, et al.
Osteoarthritis Cartilage . 2014 Sep; 23(1):103-13. PMID: 25219669
Objective: Aim of this study is to investigate the effects of Glucosamine (GlcN) and its peptidyl-derivative, 2-(N-Acetyl)-L-phenylalanylamido-2-deoxy-β-D-glucose (NAPA), on extracellular matrix (ECM) synthesis in human primary chondrocytes (HPCs). Methods: Dose-dependent...
5.
Surface analysis and osteoblasts response of a titanium oxi-carbide film deposited on titanium by ion plating plasma assisted (IPPA)
Mazzola L, Bemporad E, Misiano C, Pepe F, Santini P, Scandurra R
J Nanosci Nanotechnol . 2012 Mar; 11(10):8754-62. PMID: 22400255
Titanium is the most widely used material in orthopaedic and dental implantoprosthesis due to its superior physical properties and enhanced biocompatibility due to the spontaneous formation of a passivating layer...
6.
Cadmium-induced apoptosis and necrosis in human osteoblasts: role of caspases and mitogen-activated protein kinases pathways
Brama M, Politi L, Santini P, Migliaccio S, Scandurra R
J Endocrinol Invest . 2011 Jun; 35(2):198-208. PMID: 21697648
Cadmium is a widespread environmental pollutant which induces severe toxic alterations, including osteomalacia and osteoporosis, likely by estrogen receptor-dependent mechanisms. Indeed, cadmium has been described to act as an endocrine...
7.
Glucosamine and its N-acetyl-phenylalanine derivative prevent TNF-alpha-induced transcriptional activation in human chondrocytes
Scotto dAbusco A, Cicione C, Calamia V, Negri R, Giordano C, Grigolo B, et al.
Clin Exp Rheumatol . 2008 Jan; 25(6):847-52. PMID: 18173918
Objectives: Glucosamine (GlcN) is used in the treatment of osteoarthritis as symptomatic slow-acting drug, but its mode of action is not completely known. We analyzed the influence of GlcN and...
8.
The selective estrogen receptor modulator raloxifene regulates osteoclast and osteoblast activity in vitro
Taranta A, Brama M, Teti A, De Luca V, Scandurra R, Spera G, et al.
Bone . 2002 Feb; 30(2):368-76. PMID: 11856644
Raloxifene is a selective estrogen receptor modulator (SERM) that prevents bone loss. Although it is largely used for the treatment of osteoporosis, the mechanisms by which this compound modulates the...
9.
Molecular and biochemical characterization of the recombinant amidase from hyperthermophilic archaeon Sulfolobus solfataricus
Scotto dAbusco A, Ammendola S, Scandurra R, Politi L
Extremophiles . 2001 Jul; 5(3):183-92. PMID: 11453462
We have cloned, sequenced, and overexpressed in Escherichia coli the amidase gene from the hyperthermophilic archaeon Sulfolobus solfataricus (strain MT4). The recombinant thermophilic protein was expressed as a fusion protein...
10.
Crystallization and X-ray diffraction measurements of a thermophilic archaeal recombinant amidase from Sulfolobus solfataricus MT4
Nastopoulos V, Vallone B, Politi L, Scotto dAbusco A, Scandurra R, Tsernoglou D
Acta Crystallogr D Biol Crystallogr . 2001 Jun; 57(Pt 7):1036-7. PMID: 11418775
Recombinant amidase is a 55.8 kDa enzyme from the thermophilic archaeon Sulfolobus solfataricus MT4 that catalyses the hydrolysis of aliphatic amides of 2-6 C atoms as well as many aromatic...