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R S Swerdloff

Explore the profile of R S Swerdloff including associated specialties, affiliations and a list of published articles. Areas
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Articles 218
Citations 2334
Followers 0
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Recent Articles
1.
Anawalt B, Roth M, Ceponis J, Surampudi V, Amory J, Swerdloff R, et al.
Andrology . 2019 Apr; 7(6):878-887. PMID: 30969032
Background: Novel male-based contraceptives are needed to broaden family planning choices. A progestin, Nestorone (Nes) gel, plus a testosterone (T) gel suppresses sperm concentrations to levels associated with effective contraception...
2.
Yuen F, Wu S, Thirumalai A, Swerdloff R, Page S, Liu P, et al.
Andrology . 2018 Dec; 7(2):235-243. PMID: 30556332
Background: Testosterone (T)/Nestorone (NES) combination gel is a potential transdermal male contraceptive that suppresses gonadotropins and spermatogenesis. Transfer of transdermal T from men to women can be prevented by washing...
3.
Ayoub R, Page S, Swerdloff R, Liu P, Amory J, Leung A, et al.
Andrology . 2016 Dec; 5(2):278-285. PMID: 27907978
Dimethandrolone (DMA, 7α,11β-dimethyl-19-nortestosterone) has both androgenic and progestational activities, ideal properties for a male hormonal contraceptive. In vivo, dimethandrolone undecanoate (DMAU) is hydrolyzed to DMA. We showed previously that single...
4.
Surampudi P, Chang I, Lue Y, Doumit T, Jia Y, Atienza V, et al.
Andrology . 2015 Apr; 3(3):582-589. PMID: 25891800
Humanin (HN) has cytoprotective action on male germ cells after testicular stress induced by heat and hormonal deprivation. To examine whether HN has protective effects on chemotherapy-induced male germ cell...
5.
Nikolaenko L, Jia Y, Wang C, Diaz-Arjonilla M, Yee J, French S, et al.
Endocrinology . 2013 Nov; 155(2):417-28. PMID: 24280056
Nonalcoholic fatty liver disease is common in developed countries and is associated with obesity, metabolic syndrome, and type 2 diabetes. T deficiency is a risk factor for developing these metabolic...
6.
Roth M, Ilani N, Wang C, Page S, Bremner W, Swerdloff R, et al.
Andrology . 2013 Oct; 1(6):899-905. PMID: 24123845
Development of a male hormonal contraceptive has been challenging ascribable to the failure to adequately suppress spermatogenesis in 5-10% of men. Methods to identify incomplete suppressors early in treatment might...
7.
Lue Y, Liu P, Erkkila K, Ma K, Schwarcz M, Wang C, et al.
Int J Androl . 2009 Jul; 33(4):581-7. PMID: 19622086
XXY mouse has been characterized as an experimental model for men with Klinefelter's syndrome (XXY male phenotype). To test whether donor XY germ cells could proliferate and differentiate in the...
8.
Diaz-Arjonilla M, Schwarcz M, Swerdloff R, Wang C
Int J Impot Res . 2008 Oct; 21(2):89-98. PMID: 18843273
Obesity is an important risk factor for many common diseases including cardiovascular disease (CVD), type 2 diabetes, cancer and erectile dysfunction (ED). Adipose tissues produce a number of adipokines and...
9.
Itti E, Gaw Gonzalo I, Pawlikowska-Haddal A, Boone K, Mlikotic A, Itti L, et al.
J Clin Endocrinol Metab . 2006 Jan; 91(4):1423-7. PMID: 16403821
Context: Adults with Klinefelter's syndrome (KS) are known to present disturbances of language skills and delayed learning abilities. Objectives: The aim of this study was to assess brain morphometry in...
10.
Swerdloff R, Wang C
J Endocrinol Invest . 2005 Jul; 28(3 Suppl):112-6. PMID: 16042369
Transdermal testosterone (T) gels have proven to be an efficacious means of delivering T to hypogonadal men. Patches, gels and creams have been used in T transdermal formulations. Patches suffered...