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R R Copley

Explore the profile of R R Copley including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 9214
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Recent Articles
1.
Willis-Owen S, Shifman S, Copley R, Flint J
Mol Psychiatry . 2005 Sep; 11(2):121-2. PMID: 16189510
No abstract available.
2.
Yalcin B, Fullerton J, Miller S, Keays D, Brady S, Bhomra A, et al.
Proc Natl Acad Sci U S A . 2004 Jun; 101(26):9734-9. PMID: 15210992
Investigation of sequence variation in common inbred mouse strains has revealed a segmented pattern in which regions of high and low variant density are intermixed. Furthermore, it has been suggested...
3.
Ponting C, Mott R, Bork P, Copley R
Genome Res . 2001 Dec; 11(12):1996-2008. PMID: 11731489
Sequence database searching methods such as BLAST, are invaluable for predicting molecular function on the basis of sequence similarities among single regions of proteins. Searches of whole databases however, are...
4.
Copley R, Russell R, Ponting C
Protein Sci . 2001 Mar; 10(2):285-92. PMID: 11266614
Sequence similarity is the most common measure currently used to infer homology between proteins. Typically, homologous protein domains show sequence similarity over their entire lengths. Here we identify Asp box...
5.
Lander E, Linton L, Birren B, Nusbaum C, Zody M, Baldwin J, et al.
Nature . 2001 Mar; 409(6822):860-921. PMID: 11237011
The human genome holds an extraordinary trove of information about human development, physiology, medicine and evolution. Here we report the results of an international collaboration to produce and make freely...
6.
Gonczy P, Echeverri C, Oegema K, Coulson A, Jones S, Copley R, et al.
Nature . 2000 Dec; 408(6810):331-6. PMID: 11099034
Genome sequencing projects generate a wealth of information; however, the ultimate goal of such projects is to accelerate the identification of the biological function of genes. This creates a need...
7.
Copley R, Bork P
J Mol Biol . 2000 Oct; 303(4):627-41. PMID: 11054297
We provide statistically reliable sequence evidence indicating that at least 12 of 23 SCOP (betaalpha)(8) (TIM) barrel superfamilies share a common origin. This includes all but one of the known...
8.
Schultz J, Doerks T, Ponting C, Copley R, Bork P
Nat Genet . 2000 Jun; 25(2):201-4. PMID: 10835637
Cloning procedures aided by homology searches of EST databases have accelerated the pace of discovery of new genes, but EST database searching remains an involved and onerous task. More than...
9.
Ponting C, Schultz J, Copley R, Andrade M, Bork P
Adv Protein Chem . 2000 Jun; 54:185-244. PMID: 10829229
No abstract available.
10.
Copley R, Ponting C, Bork P
Curr Biol . 2000 Mar; 9(19):R718-9. PMID: 10712041
No abstract available.