R P McGuinness
Overview
Explore the profile of R P McGuinness including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
120
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Recent Articles
1.
McGuinness R, Proctor J, GALLANT D, van Staden C, Ly J, Tang F, et al.
Comb Chem High Throughput Screen
. 2009 Jun;
12(8):812-23.
PMID: 19531008
Drug discovery efforts advance in step with advancements in assay technologies, as new technologies provide new lenses through which biology can be viewed. The novel information gathered results in the...
2.
McGuinness R, Ge Y, Patel S, Kashmiri S, Lee H, HAND P, et al.
Hum Gene Ther
. 1999 Feb;
10(2):165-73.
PMID: 10022542
A chimeric immune receptor consisting of an extracellular antigen-binding domain derived from the CC49 humanized single-chain antibody, linked to the CD3zeta signaling domain of the T cell receptor, was generated...
3.
Jakobovits A, Green L, Hardy M, Tsuda H, Louie D, Mendez M, et al.
Ann N Y Acad Sci
. 1995 Sep;
764:525-35.
PMID: 7486581
Our paper describes the introduction of large fragments of both the human heavy and light chain Ig genes into the mouse germline to create a mouse strain capable of producing...
4.
Green L, Hardy M, Tsuda H, Louie D, Mendez M, Abderrahim H, et al.
Nat Genet
. 1994 May;
7(1):13-21.
PMID: 8075633
We describe a strategy for producing human monoclonal antibodies in mice by introducing large segments of the human heavy and kappa light chain loci contained on yeast artificial chromosomes into...
5.
Jakobovits A, Vergara G, Kennedy J, Hales J, McGuinness R, Brenner D, et al.
Proc Natl Acad Sci U S A
. 1993 Mar;
90(6):2551-5.
PMID: 8460171
Using a recently described method for efficiently deriving homozygous targeted alleles in embryonic stem cells, we produced chimeric mice whose tissues were derived partially from embryonic stem cells bearing homozygous...
6.
McGuinness R, Moran F
J Reprod Immunol
. 1992 Jan;
21(1):29-46.
PMID: 1734076
The cellular immune response of mice to porcine and rat zona pellucida and cynomolgus macaques to porcine zona pellucida antigens was evaluated. Mice mounted a vigorous cellular response to both...
7.
VandeVoort C, McGuinness R, Overstreet J, OHern P, Goldberg E
Am J Reprod Immunol
. 1990 Sep;
24(1):1-8.
PMID: 2285453
The goals of this study were to determine the site at which fertility is impaired in mice immunized with LDH-C4 and to determine whether immunization of both males and females...