R Ossenkoppele
Overview
Explore the profile of R Ossenkoppele including associated specialties, affiliations and a list of published articles.
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12
Citations
881
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Recent Articles
1.
Bethlehem R, Seidlitz J, White S, Vogel J, Anderson K, Adamson C, et al.
Nature
. 2022 Sep;
610(7931):E6.
PMID: 36151472
No abstract available.
2.
Bethlehem R, Seidlitz J, White S, Vogel J, Anderson K, Adamson C, et al.
Nature
. 2022 Apr;
604(7906):525-533.
PMID: 35388223
Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, no reference standards currently exist to quantify individual...
3.
Singleton E, Pijnenburg Y, Gami-Patel P, Boon B, Bouwman F, Papma J, et al.
Alzheimers Res Ther
. 2022 Jan;
14(1):11.
PMID: 35057846
Background: The neurobiological origins of the early and predominant behavioral changes seen in the behavioral variant of Alzheimer's disease (bvAD) remain unclear. A selective loss of Von Economo neurons (VENs)...
4.
Ashton N, Leuzy A, Karikari T, Mattsson-Carlgren N, Dodich A, Boccardi M, et al.
Eur J Nucl Med Mol Imaging
. 2021 Mar;
48(7):2140-2156.
PMID: 33677733
Purpose: The development of blood biomarkers that reflect Alzheimer's disease (AD) pathophysiology (phosphorylated tau and amyloid-β) has offered potential as scalable tests for dementia differential diagnosis and early detection. In...
5.
Leuzy A, Ashton N, Mattsson-Carlgren N, Dodich A, Boccardi M, Corre J, et al.
Eur J Nucl Med Mol Imaging
. 2021 Mar;
48(7):2121-2139.
PMID: 33674895
Purpose: In the last decade, the research community has focused on defining reliable biomarkers for the early detection of Alzheimer's disease (AD) pathology. In 2017, the Geneva AD Biomarker Roadmap...
6.
Wolters E, Dodich A, Boccardi M, Corre J, Drzezga A, Hansson O, et al.
Eur J Nucl Med Mol Imaging
. 2021 Feb;
48(7):2097-2109.
PMID: 33547556
Purpose: In 2017, the Geneva Alzheimer's disease (AD) Biomarker Roadmap initiative adapted the framework of the systematic validation of oncological diagnostic biomarkers to AD biomarkers, with the aim to accelerate...
7.
Wolters E, van de Beek M, Ossenkoppele R, Golla S, Verfaillie S, Coomans E, et al.
Neuroimage Clin
. 2021 Jan;
28:102504.
PMID: 33395993
Purpose: Alpha-synuclein often co-occurs with Alzheimer's disease (AD) pathology in Dementia with Lewy Bodies (DLB). From a dynamic [F]flortaucipir PET scan we derived measures of both tau binding and relative...
8.
van Loenhoud A, Habeck C, van der Flier W, Ossenkoppele R, Stern Y
Neuroimage
. 2020 Feb;
210:116593.
PMID: 32007499
Cognitive reserve (CR) is thought to protect against the consequence of age- or disease-related structural brain changes across multiple cognitive domains. The neural basis of CR may therefore comprise a...
9.
van Loenhoud A, de Boer C, Wols K, Pijnenburg Y, Lemstra A, Bouwman F, et al.
Alzheimers Res Ther
. 2019 Dec;
11(1):112.
PMID: 31882022
Background: Growing evidence suggests a role of occupation in the emergence and manifestation of dementia. Occupations are often defined by complexity level, although working environments and activities differ in several...
10.
Scheltens P, Zwan M, Ossenkoppele R, Bouwman F, van Berckel B
Ned Tijdschr Geneeskd
. 2017 Feb;
161:D808.
PMID: 28145213
Until a few years ago, amyloid plaques in the brains of patients with Alzheimer's disease could only be demonstrated by means of neuropathological examination. New PET tracers allow for visualisation...