R Nave
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Explore the profile of R Nave including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
596
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Recent Articles
1.
Nave R, Hochel J, Mellinger U, Kohnke A, Elliesen J, Schmitz H
Hum Reprod
. 2020 Sep;
35(11):2515-2523.
PMID: 32914172
Study Question: What is the reason for insufficient contraceptive efficacy of levonorgestrel (LNG) delivered by intravaginal ring (IVR) releasing comparable amounts of LNG as approved progestogen-only pills (POPs)? Summary Answer:...
2.
Surface ruptures database related to the 26 December 2018, M 4.9 Mt. Etna earthquake, southern Italy
Villani F, Pucci S, Azzaro R, Civico R, Cinti F, Pizzimenti L, et al.
Sci Data
. 2020 Feb;
7(1):42.
PMID: 32034156
We provide a database of the surface ruptures produced by the 26 December 2018 Mw 4.9 earthquake that struck the eastern flank of Mt. Etna volcano in Sicily (southern Italy)....
3.
Schultze-Mosgau M, Waellnitz K, Nave R, Klein S, Kraetzschmar J, Rautenberg T, et al.
Hum Reprod
. 2016 Jul;
31(8):1713-22.
PMID: 27390369
Study Question: What are suitable doses of the aromatase inhibitor anastrozole (ATZ) and the progestin levonorgestrel (LNG), when delivered to the systemic circulation by an intravaginal ring (IVR), for further...
4.
Boss H, Minic P, Nave R
Clin Med Insights Pediatr
. 2013 Jun;
4:1-10.
PMID: 23761990
Background: Ciclesonide is an inhaled corticosteroid administered by a metered dose inhaler (MDI) to treat bronchial asthma. After inhalation, the inactive ciclesonide is converted by esterases in the airways to...
5.
Oliven A, Nave R, Gilad D, Barch A
Stud Health Technol Inform
. 2011 Sep;
169:233-7.
PMID: 21893748
Structured Clinical Examinations (OSCE) are resource intensive, not practical as teaching tools, and their reliability depends on evaluators. Computer-based case simulations ("virtual patients", VP) have been advocated as useful and...
6.
Nave R, Watz H, Hoffmann H, Boss H, Magnussen H
Eur Respir J
. 2010 Mar;
36(5):1113-9.
PMID: 20351025
Ciclesonide is an inhaled corticosteroid, administered as a prodrug via a metered-dose inhaler. Following deposition in the lung, ciclesonide is hydrolysed by esterases to form the pharmacologically active metabolite desisobutyryl-ciclesonide...
7.
Sato H, Nave R, Nonaka T, Mochizuki T, Takahama S, Kondo S
Biopharm Drug Dispos
. 2006 Dec;
28(2):59-64.
PMID: 17163410
Ciclesonide, a new corticosteroid for allergic rhinitis, is administered as an inactive parent compound that is converted by esterases to the pharmacologically active metabolite, desisobutyryl-ciclesonide (des-CIC). This study investigated the...
8.
Derendorf H, Nave R, Drollmann A, Cerasoli F, Wurst W
Eur Respir J
. 2006 Nov;
28(5):1042-50.
PMID: 17074919
The pharmacokinetic and pharmacodynamic effects of inhaled corticosteroids (ICS) have shaped the efficacy and safety of these agents in the treatment of asthma. Important pharmacokinetic and pharmacodynamic characteristics that can...
9.
Peet C, Enos T, Nave R, Zech K, Hall M
Eur J Drug Metab Pharmacokinet
. 2006 Jan;
30(4):275-86.
PMID: 16435573
Ciclesonide, a novel inhaled corticosteroid, is currently being developed for the treatment of asthma. Here, the enzymes catalysing the human hepatic metabolism of ciclesonide were investigated. When incubated with human...
10.
Nave R, Gunawardena K, Zech K, Bethke T
Int J Clin Pharmacol Ther
. 2006 Jan;
44(1):1-7.
PMID: 16425964
Objective: To evaluate whether the inflammatory process and bronchial constriction associated with asthma influence the pulmonary distribution and airway penetration of inhaled ciclesonide by investigating the pharmacokinetics of ciclesonide and...