R Michael Roberts
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Explore the profile of R Michael Roberts including associated specialties, affiliations and a list of published articles.
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112
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3266
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Recent Articles
1.
2.
Yu J, Zheng Y, Sheridan M, Ezashi T, Roberts R, Liu S
bioRxiv
. 2025 Jan;
PMID: 39803534
Zika virus (ZIKV) infection can lead to a variety of clinical outcomes, including severe congenital abnormalities. The phosphatidylserine (PS) receptors AXL and TIM-1 are recognized as critical entry factors for...
3.
Kinkade J, Singh P, Verma M, Khan T, Ezashi T, Bivens N, et al.
Cells
. 2024 Nov;
13(22).
PMID: 39594615
In mice, the fetal brain is dependent upon the placenta for factors that guide its early development. This linkage between the two organs has given rise to the term, the...
4.
Lyu Z, Kinkade J, Bivens N, Roberts R, Joshi T, Rosenfeld C
Proc Natl Acad Sci U S A
. 2024 Oct;
121(45):e2412349121.
PMID: 39475633
Pregnant women are often prescribed or abuse opioid drugs. The placenta is likely the key to understanding how opioids cause adverse pregnancy outcomes. Maternal oxycodone (OXY) exposure of pregnant mice...
5.
Logsdon D, Ming H, Ezashi T, West R, Schoolcraft W, Roberts R, et al.
Biol Reprod
. 2024 Aug;
111(5):1000-1016.
PMID: 39109839
Mechanisms controlling trophoblast (TB) proliferation and differentiation during embryo implantation are poorly understood. Human trophoblast stem cells (TSC) and BMP4/A83-01/PD173074-treated pluripotent stem cell-derived trophoblast cells (BAP) are two widely employed,...
6.
Khan T, Whyte J, Schulz L, Roberts R
Placenta
. 2024 Jun;
PMID: 38944560
Large, multinucleated cells, like syncytiotrophoblasts (STB), are not readily analyzed by standard methods used for single cells, such as single-cell RNA-sequencing and fluorescence-activated cellular sorting (FACS). Here we have demonstrated...
7.
Kinkade J, Seetharam A, Sachdev S, Bivens N, Phinney B, Grigorean G, et al.
Biol Reprod
. 2023 Oct;
110(2):310-328.
PMID: 37883444
The fetal brain of the mouse is thought to be dependent upon the placenta as a source of serotonin (5-hydroxytryptamine; 5-HT) and other factors. How factors reach the developing brain...
8.
Amargant F, Zhou L, Yuan Y, Nahar A, Krisher R, Spate L, et al.
Hum Reprod
. 2023 Aug;
38(10):1938-1951.
PMID: 37608600
Study Question: Does a chemically defined maturation medium supplemented with FGF2, LIF, and IGF1 (FLI) improve in vitro maturation (IVM) of cumulus-oocyte complexes (COCs) obtained from children, adolescents, and young...
9.
Zhang J, Yang W, Roy S, Liu H, Roberts R, Wang L, et al.
Proc Natl Acad Sci U S A
. 2023 Apr;
120(17):e2218623120.
PMID: 37068248
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spreads efficiently by spike-mediated, direct cell-to-cell transmission. However, the underlying mechanism is poorly understood. Herein, we demonstrate that the tight junction protein occludin...
10.
Zhu L, Zhou T, Iyyappan R, Ming H, Dvoran M, Wang Y, et al.
Development
. 2022 Oct;
149(21).
PMID: 36227586
High-resolution ribosome fractionation and low-input ribosome profiling of bovine oocytes and preimplantation embryos has enabled us to define the translational landscapes of early embryo development at an unprecedented level. We...