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R Metherate

Explore the profile of R Metherate including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
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Recent Articles
1.
Kaur S, Rose H, Lazar R, Liang K, Metherate R
Neuroscience . 2005 Jun; 134(3):1033-45. PMID: 15979241
Auditory cortex neurons integrate information over a broad range of sound frequencies, yet it is not known how such integration is accomplished at the cellular or systems levels. Whereas information...
2.
Rose H, Metherate R
Neuroscience . 2001 Sep; 106(2):331-40. PMID: 11566504
Stimulation of the medial geniculate body in an auditory thalamocortical slice elicits a short-latency current sink in the middle cortical layers, as would be expected following activation of thalamocortical relay...
3.
Cruikshank S, Killackey H, Metherate R
Neuroscience . 2001 Aug; 105(3):553-69. PMID: 11516823
The calcium binding proteins parvalbumin and calbindin are thought to differentially regulate physiological functions and often show complementary distributions in the CNS. Our goal was to determine parvalbumin and calbindin...
4.
Hsieh C, Cruikshank S, Metherate R
Brain Res . 2000 Oct; 880(1-2):51-64. PMID: 11032989
To investigate synaptic mechanisms underlying information processing in auditory cortex, we examined cholinergic modulation of synaptic transmission in a novel slice preparation containing thalamocortical and intracortical inputs to mouse auditory...
5.
Aramakis V, Hsieh C, Leslie F, Metherate R
J Neurosci . 2000 Aug; 20(16):6106-16. PMID: 10934260
Cholinergic markers in the middle layers of rat auditory cortex are transiently upregulated during the second postnatal week, at which time alpha 7 nicotinic acetylcholine receptors (nAChRs) selectively regulate NMDA...
6.
Metherate R, Aramakis V
Brain Res Dev Brain Res . 1999 Jul; 115(2):131-44. PMID: 10407131
During early postnatal life, several critical events contribute to the functional development of rat sensory neocortex. Thalamocortical innervation of sensory cortex is completed during the first postnatal week and extrathalamic...
7.
Metherate R, Cruikshank S
Exp Brain Res . 1999 Jun; 126(2):160-74. PMID: 10369139
To investigate how auditory cortex responds to thalamic inputs, we have used electrophysiological and anatomical techniques to characterize a brain slice containing functionally linked thalamocortical and intracortical pathways. In extracellular...
8.
Aramakis V, Metherate R
J Neurosci . 1998 Oct; 18(20):8485-95. PMID: 9763491
The neurotransmitters acetylcholine (ACh) and glutamate have been separately implicated in synaptic plasticity during development of sensory neocortex. Here we show that these neurotransmitters can, in fact, act synergistically via...
9.
Metherate R
Front Biosci . 1998 May; 3:d494-501. PMID: 9569228
Neurons in the auditory cortex (AC) respond to acoustic stimuli in diverse ways. Short latency responses code for the physical properties of stimuli, i.e., their frequency and intensity, whereas longer...
10.
Metherate R, Ashe J
Brain Res . 1995 Nov; 699(2):221-30. PMID: 8616625
We have investigated the regulation of an N-methyl-D-aspartate (NMDA) receptor-mediated synaptic potential by gamma-aminobutyric acid (GABA)-mediated inhibition using extracellular and whole-cell voltage clamp recordings in rat auditory cortex in vitro....